Single-cell modeling of chromosomal organization could help scientists untangle how genomic organization informs function and vice versa.
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References
Nagano, T. et al. Single-cell Hi-C reveals cell-to-cell variability in chromosome structure. Nature 502, 59–64 (2013).
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Eisenstein, M. Finding function in the folds. Nat Methods 10, 1052–1053 (2013). https://doi.org/10.1038/nmeth.2716
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DOI: https://doi.org/10.1038/nmeth.2716