A new study shows that astrocytes are involved in the development of chronic itch in a mouse model. This is dependent on upregulation of lipocalin 2 (LCN2) by the transcription factor STAT-3 and astrogliosis.
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Green, D., Dong, X. Supporting itch: a new role for astrocytes in chronic itch. Nat Med 21, 841–842 (2015). https://doi.org/10.1038/nm.3921
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DOI: https://doi.org/10.1038/nm.3921
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