Cross-presentation of antigens is essential for the responses of cytotoxic T cells to tumors and viruses. Two new papers offer insights into the subcellular compartment and types of dendritic cells that mediate cross-presentation.
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Kasturi, S., Pulendran, B. Cross-presentation: avoiding trafficking chaos?. Nat Immunol 9, 461–463 (2008). https://doi.org/10.1038/ni0508-461
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DOI: https://doi.org/10.1038/ni0508-461
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