Adenosine produced by apoptotic regulatory T cells (Treg cells) has a more important immunosuppressive role in the tumor microenvironment than that of live Treg cells. This discovery raises the possibility of novel strategies for cancer immunotherapy.
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Togashi, Y., Nishikawa, H. Suppression from beyond the grave. Nat Immunol 18, 1285–1286 (2017). https://doi.org/10.1038/ni.3870
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DOI: https://doi.org/10.1038/ni.3870
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