Infection with an RNA virus induces the interferons IFN-β and IFN-λ via the adaptor MAVS located in mitochondria, while peroxisomal MAVS selectively activates an IFN-λ response.
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Ding, S., Robek, M. Peroxisomal MAVS activates IRF1-mediated IFN-λ production. Nat Immunol 15, 700–701 (2014). https://doi.org/10.1038/ni.2924
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DOI: https://doi.org/10.1038/ni.2924
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