A unique complex of the interferon receptor IFNAR1 and interferon-β (IFN-β) has been identified that signals independently of IFNAR2 and induces a distinct set of interferon-inducible genes and downstream IFN-β-specific functional responses.
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Kaur, S., Platanias, L. IFN-β-specific signaling via a unique IFNAR1 interaction. Nat Immunol 14, 884–885 (2013). https://doi.org/10.1038/ni.2686
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DOI: https://doi.org/10.1038/ni.2686
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