Diseased host cells are eliminated more effectively when natural killer cells grow up in the presence of classical major histocompatibility complex (MHC) class I molecules. The nonclassical MHC class I molecule H2-M3 can exert an analogous effect.
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NK cell education via nonclassical MHC and non-MHC ligands
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References
Andrews, D.M. et al. Nat. Immunol. 13, 1171–1177 (2012).
Karlhofer, F.M., Ribaudo, R.K. & Yokoyama, W.M. Nature 358, 66–70 (1992).
Kim, S. et al. Nature 436, 709–713 (2005).
Doucey, M.A. et al. Nat. Immunol. 5, 328–336 (2004).
Chalifour, A. et al. Immunity 30, 337–347 (2009).
Joncker, N.T., Shifrin, N., Delebecque, F. & Raulet, D.H. J. Exp. Med. 207, 2065–2082 (2010).
Chiu, N.M., Chun, T., Fay, M., Mandal, M. & Wang, C.R. J. Exp. Med. 190, 423–434 (1999).
Lakshmikanth, T. et al. J. Clin. Invest. 119, 1251–1263 (2009).
Xu, H., Chun, T., Choi, H.J., Wang, B. & Wang, C.R. J. Exp. Med. 203, 449–459 (2006).
Anfossi, N. et al. J. Immunol. 173, 3773–3782 (2004).
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Held, W. Nonclassical NK cell education. Nat Immunol 13, 1135–1137 (2012). https://doi.org/10.1038/ni.2470
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DOI: https://doi.org/10.1038/ni.2470
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