News & Views

Polycomb silencing mediated by specific DNA-binding recruiters

Regulation of epigenetic factors through their recruitment to specific genomic regions is still poorly understood. A recent study demonstrates a global mechanism of tethering Polycomb group (PcG) proteins through sequence-specific DNA-binding factors.

  • Subscribe to Nature Genetics for full access:

    $59

    Subscribe

Additional access options:

Already a subscriber?  Log in  now or  Register  for online access.

References

  1. 1.

    & Annu. Rev. Plant Biol. 66, 269–296 (2015).

  2. 2.

    & Mol. Cell 49, 808–824 (2013).

  3. 3.

    , & Chromosoma 125, 471–496 (2016).

  4. 4.

    & Adv. Genet. 81, 83–118 (2013).

  5. 5.

    et al. BMC Genomics 14, 593 (2013).

  6. 6.

    et al. Plant Physiol. 168, 1013–1024 (2015).

  7. 7.

    et al. Plant Cell Physiol. 58, 607–621 (2017).

  8. 8.

    et al. Nat. Genet. 49, 1546–1552 (2017).

  9. 9.

    & Nat. Struct. Mol. Biol. 19, 1214–1215 (2012).

  10. 10.

    & Science 331, 76–79 (2011).

  11. 11.

    et al. Science 343, 1248559 (2014).

Download references

Author information

Affiliations

  1. Eduardo March and Sara Farrona are in the Plant & Agricultural Biosciences Centre (PABC), National University of Ireland Galway, Galway, Ireland.

    • Eduardo March
    •  & Sara Farrona

Authors

  1. Search for Eduardo March in:

  2. Search for Sara Farrona in:

Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Sara Farrona.