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Should opioids be prescribed to treat patients with osteoarthritis?

Nature Clinical Practice Rheumatology volume 4, pages 180–181 (2008)Cite this article

boxed-textAvouac J et al. (2007) Efficacy and safety of opioids for osteoarthritis: a meta-analysis of randomized controlled trials. Osteoarthritis Cartilage 15: 957–965

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References

  1. Cepeda MS et al. (2007) Tramadol for osteoarthritis: a systematic review and metaanalysis. J Rheumatol 34: 543–555

    CAS  PubMed  Google Scholar 

  2. Cepeda MS et al. (2005) Comparison of morphine, ketorolac, and their combination for postoperative pain: results from a large, randomized, double-blind trial. Anesthesiology 103: 1225–1232

    Article  CAS  Google Scholar 

  3. Martell BA et al. (2007) Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction. Ann Intern Med 146: 116–127

    Article  Google Scholar 

  4. Ballantyne JC and Mao J (2003) Opioid therapy for chronic pain. N Engl J Med 349: 1943–1953

    Article  CAS  Google Scholar 

  5. King T et al. (2007) Morphine treatment accelerates sarcoma-induced bone pain, bone loss, and spontaneous fracture in a murine model of bone cancer. Pain 132: 154–168

    Article  CAS  Google Scholar 

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Acknowledgements

The synopsis was written by Lisa Richards, Editorial Assistant, Nature Clinical Practice.

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  1. Department of Anesthesiology, Tufts-New England Medical Center, 750 Washington Street, Box 298, Boston, MA 02111, USA scepeda@tufts-nemc.org

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  1. M Soledad Cepeda is a Professor in the Department of Anesthesiology at Tufts-New England Medical Center, Boston, MA, USA.,

    M Soledad Cepeda

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Cepeda, M. Should opioids be prescribed to treat patients with osteoarthritis?. Nat Rev Rheumatol 4, 180–181 (2008). https://doi.org/10.1038/ncprheum0758

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