Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Practice Point
  • Published:

Hyperuricemia treatment: is creatinine clearance a safer allopurinol dosing meter than plasma creatinine levels?

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Bieber JD and Terkeltaub RA (2004) Gout: on the brink of novel therapeutic options for an ancient disease. Arthritis Rheum 50: 2400–2414

    Article  Google Scholar 

  2. Wallace KL et al. (2004) Increasing prevalence of gout and hyperuricemia over 10 years among older adults in a managed care population. J Rheumatol 31: 1582–1587

    PubMed  Google Scholar 

  3. Terkeltaub RA (2003) Clinical practice. Gout. N Engl J Med 349: 1647–1655

    Article  CAS  Google Scholar 

  4. Yamanaka H et al. (1998) Optimal range of serum urate concentrations to minimize risk of gouty attacks during anti-hyperuricemic treatment. Adv Exp Med Biol 431: 13–18

    Article  CAS  Google Scholar 

  5. Li-Yu J et al. (2001) Treatment of chronic gout. Can we determine when urate stores are depleted enough to prevent attacks of gout? J Rheumatol 28: 577–580

    CAS  PubMed  Google Scholar 

Download references

Acknowledgements

The synopsis was written by Jasmine Farsarakis, Associate Editor, Nature Clinical Practice.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Robert Terkeltaub.

Ethics declarations

Competing interests

Dr Terkeltaub serves as a paid consultant to Abbott and TAP Pharmaceuticals and receives research-grant support from Novartis and Eli Lilly Pharmaceuticals.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Terkeltaub, R. Hyperuricemia treatment: is creatinine clearance a safer allopurinol dosing meter than plasma creatinine levels?. Nat Rev Rheumatol 2, 68–69 (2006). https://doi.org/10.1038/ncprheum0099

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncprheum0099

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing