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Sunitinib-related cardiotoxicity: an interdisciplinary issue

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References

  1. Ewer MS et al. (2005) Reversibility of trastuzumab–related cardiotoxicity: new insights based on clinical course and response to medical treatment. J Clin Oncol 23: 7820–7826

    Article  CAS  Google Scholar 

  2. Kerkela R et al. (2006) Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nat Med 12: 908–916

    Article  Google Scholar 

  3. Yeh ET et al. (2004) Cardiovascular complications of cancer therapy: diagnosis, pathogenesis, and management. Circulation 109: 3122–3131

    Article  Google Scholar 

  4. Khakoo AY et al. (2008) Heart failure associated with sunitinib malate, a multi-targeted receptor tyrosine kinase inhibitor. Cancer [10.1002/cncr.23460]

  5. Ewer MS and Lenihan DJ (2008) Left ventricular ejection fraction and cardiotoxicity: is our ear really to the ground? J Clin Oncol 26: 1201–1203

    Article  Google Scholar 

  6. Chien KR (2006) Herceptin and the heart—a molecular modifier of cardiac failure. N Engl J Med 354: 789–790

    Article  CAS  Google Scholar 

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Acknowledgements

The synopsis was written by Alexandra King, Associate Editor, Nature Clinical Practice.

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Correspondence to Michael S Ewer.

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The authors declare no competing financial interests.

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Ewer, M., Lenihan, D. & Khakoo, A. Sunitinib-related cardiotoxicity: an interdisciplinary issue. Nat Rev Cardiol 5, 364–365 (2008). https://doi.org/10.1038/ncpcardio1222

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