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Does carotid endarterectomy prevent disabling and fatal strokes in neurologically asymptomatic subjects?

Nature Clinical Practice Cardiovascular Medicine volume 1, pages 20–21 (2004)Cite this article

boxed-textHalliday A et al. MRC Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group (2004) Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomized controlled trial. Lancet 363: 1491–1502

Provided centers have perioperative stroke and mortality rates <3%, CEA may be superior to nonoperative management in asymptomatic patients with 60–99% carotid stenosis by duplex scanning

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References

  1. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study (1995) Endarterectomy for asymptomatic carotid artery stenosis. JAMA 273: 1421–1428

  2. Hertzer NR (1996) A personal view: the Asymptomatic Carotid Atherosclerosis Study results – read the label carefully. J Vasc Surg 23: 167–171

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Acknowledgements

The synopsis was written by Ruth Kirby, Research Highlights Editor, Nature Clinical Practice

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  1. NR Hertzer is a member and former Chairman of the Department of Vascular Surgery at the Cleveland Clinic Foundation, Cleveland, OH, USA

    Norman R Hertzer

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  1. Norman R Hertzer
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Correspondence to Norman R Hertzer.

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The author declares no competing financial interests.

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Hertzer, N. Does carotid endarterectomy prevent disabling and fatal strokes in neurologically asymptomatic subjects?. Nat Rev Cardiol 1, 20–21 (2004). https://doi.org/10.1038/ncpcardio0008

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