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Plant signaling

Abscisic acid receptor hole-in-one

The phytohormone abscisic acid (ABA) has a central role in adaptive responses of plants to abiotic stress. A new ABA antagonist offers a promising tool to study ABA signaling and adaptation to abiotic stress in diverse plants, including crops.

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Figure 1: The ABA antagonist AS6 was rationally designed to bind PYL in a similar configuration to ABA.

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Correspondence to Ken-ichiro Hayashi.

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The authors declare no competing financial interests.

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Hayashi, Ki., Kinoshita, T. Abscisic acid receptor hole-in-one. Nat Chem Biol 10, 414–415 (2014). https://doi.org/10.1038/nchembio.1529

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