An inhibitor of the deubiquitinase complex USP1-UAF1 highlights the requirement for reversible ubiquitination in DNA repair pathways that are critical for human development and disease.
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Locke, M., Rape, M. Walking the edge. Nat Chem Biol 10, 243–244 (2014). https://doi.org/10.1038/nchembio.1483
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DOI: https://doi.org/10.1038/nchembio.1483