Cholic acid and 24(S),25-epoxycholesterol are oxysterols detected in the developing mesencephalic tissue and selectively regulate the production of either the red nucleus or dopaminergic neurons via activation of the liver X receptors.
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Katie Vicari
References
Lees, A.J., Hardy, J. & Revesz, T. Lancet 373, 2055–2066 (2009).
Lindvall, O. & Bjorklund, A. Neurotherapeutics 8, 539–548 (2011).
Theofilopoulos, S. et al. Nat. Chem. Biol. 9, 126–133 (2013).
Bensinger, S.J. & Tontonoz, P. Nature 454, 470–477 (2008).
Janowski, B.A. et al. Proc. Natl. Acad. Sci. USA 96, 266–271 (1999).
Dai, Y.B. et al. Proc. Natl. Acad. Sci. USA 109, 13112–13117 (2012).
Sacchetti, P. et al. Cell Stem Cell 5, 409–419 (2009).
Ang, S.L. Development 133, 3499–3506 (2006).
Kriks, S. et al. Nature 480, 547–551 (2011).
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Broccoli, V., Caiazzo, M. Oxysterols detour to neurodevelopment. Nat Chem Biol 9, 70–71 (2013). https://doi.org/10.1038/nchembio.1165
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DOI: https://doi.org/10.1038/nchembio.1165
