A sophisticated palladium(IV)-based species allows nucleophilic fluoride to react as an electrophilic fluorination reagent. This long-awaited reactivity will be especially useful in the preparation of radiochemically labelled molecules for positron emission tomography studies.
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Gouverneur, V. Flipping fluoride's reactivity. Nature Chem 4, 152–154 (2012). https://doi.org/10.1038/nchem.1280
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DOI: https://doi.org/10.1038/nchem.1280
