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A nexus for receptor recycling

Sorting nexin proteins (SNXs) and the cargo-selective retromer complex play key roles in receptor recycling from endosomes to the cell surface. A global proteomics analysis reveals a collection of cell surface proteins that rely on SNX27 and the retromer complex for their cell surface localization at steady state.

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Figure 1: Complexity in endocytic receptor trafficking.

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Correspondence to Suzanne R. Pfeffer.

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Pfeffer, S. A nexus for receptor recycling. Nat Cell Biol 15, 446–448 (2013). https://doi.org/10.1038/ncb2751

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