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PrePAIRing Cas9s for screening success

Nature Biotechnology volume 36, pages 147–148 (2018)Cite this article

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Orthogonal CRISPR–Cas9 nucleases enable more efficient high-throughput screens for deciphering genetic interactions.

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Figure 1: Using orthogonal CRISPR–Cas9 proteins for high-throughput genetic screens.

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Authors and Affiliations

  1. Zhuo Zhou and Wensheng Wei are in the Biodynamics Optical Imaging Center (BIOPIC), Beijing Advanced Innovation Center for Genomics, Peking-Tsinghua Center for Life Sciences, State Key Laboratory of Protein and Plant Gene Research, and School of Life Sciences, Peking University, Beijing, China.,

    Zhuo Zhou & Wensheng Wei

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  1. Zhuo Zhou
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  2. Wensheng Wei
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Corresponding authors

Correspondence to Zhuo Zhou or Wensheng Wei.

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Competing interests

Wensheng Wei is the founder of EdiGene Inc. that offers CRISPR screens.

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Zhou, Z., Wei, W. PrePAIRing Cas9s for screening success. Nat Biotechnol 36, 147–148 (2018). https://doi.org/10.1038/nbt.4075

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