T cells of the immune system mount antiviral responses, but if a response fails, a chronic viral infection can develop. It now seems that a T-cell subset in lymphoid immune tissues can control chronic infection. See Letters p.412 & p.417
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References
Im, S. J. et al. Nature 537, 417–421 (2016).
He, R. et al. Nature 537, 412–416 (2016).
Leong, Y. A. et al. Nature Immunol. http://dx.doi.org/10.1038/ni.3543 (2016).
Cui, W. & Kaech, S. M. Immunol. Rev. 236, 151–166 (2010).
Fukazawa, Y. et al. Nature Med. 21, 132–139 (2015).
Tangye, S. G., Ma, C. S., Brink, R. & Deenick, E. K. Nature Rev. Immunol. 13, 412–426 (2013).
Crotty, S. Immunity 41, 529–542 (2014).
Crotty, S. Annu. Rev. Immunol. 29, 621–663 (2011).
Forster, R., Emrich, T., Kremmer, E. & Lipp, M. Blood 84, 830–840 (1994).
Quigley, M. F., Gonzalez, V. D., Granath, A., Andersson, J. & Sandberg, J. K. Eur. J. Immunol. 37, 3352–3362 (2007).
Wherry, E. J. & Kurachi, M. Nature Rev. Immunol. 15, 486–499 (2015).
Choi, Y. S. et al. Nature Immunol. 16, 980–990 (2015).
Shaw, L. A. et al. Nature Immunol. 17, 834–843 (2016).
Topalian, S. L., Drake, C. G. & Pardoll, D. M. Cancer Cell 27, 450–461 (2015).
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Ma, C., Tangye, S. Cytotoxic T cells that escape exhaustion. Nature 537, 312–314 (2016). https://doi.org/10.1038/nature19428
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DOI: https://doi.org/10.1038/nature19428
