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Insights into different populations’ immune responses to SARS-CoV-2 infection

Analysis of immune responses to SARS-CoV-2 at single-cell resolution reveals marked differences across human populations that are caused by previous infections and genetic variation. Natural selection and past reproduction with Neanderthals contributed to these differing immune responses and disparities in COVID-19 risk.

This is a summary of: Aquino, Y. et al. Dissecting human population variation in single-cell responses to SARS-CoV-2. Nature https://doi.org/10.1038/s41586-023-06422-9 (2023).

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doi: https://doi.org/10.1038/d41586-023-02378-y

‘Expert opinion’ and the figure are published under a CC BY 4.0 licence.

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