CORRESPONDENCE

A repository for quality-assured data on enzyme activity

On behalf of the STRENDA Commission, Beilstein Institute for the Advancement of Chemical Sciences, Frankfurt am Main, Germany.

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On behalf of the STRENDA Commission, Beilstein Institute for the Advancement of Chemical Sciences, Frankfurt am Main, Germany.
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Transparent reporting of experimental methods to ensure the reproducibility of results (see Nature 555, 6; 2018) is particularly crucial in enzyme kinetics, given the wide variation in many assay parameters. It also allows unambiguous interpretation of the data.

The STRENDA (Standards for Reporting Enzymology Data) database is a repository for published enzymology data, lodged under its guidelines for transparent reporting of experimental methods. The STRENDA Commission is working with the biochemistry community and funding agencies to make submission to this database routine practice during publication. More than 50 journals currently recommend the guidelines to their authors.

The implementation of scientific data standards has typically been left to data curators (see, for example, U. Wittig et al. Nucl. Acids Res. 46, D656–D660; 2018). The STRENDA database now serves as a formal validation tool for reliable reporting of data (see also N. Swainston et al. FEBS J. https://doi.org/cm8d; 2018).

We suggest that our model could be adapted for the benefit of authors, reviewers, data consumers, publishers and funders across experimental disciplines.

Nature 556, 309 (2018)

doi: 10.1038/d41586-018-04630-2
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