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Cancer metabolism

A waste of insulin interference

Nature volume 521, pages 430–431 (2015)Cite this article

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Many people with cancer die from a wasting disorder called cancer-associated cachexia. Two studies in fruit flies show that inhibition of insulin signalling causes cachexia-like organ wasting.

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Figure 1: Systemic metabolic changes in cancer.

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Authors and Affiliations

  1. Erwin F. Wagner is in the Cancer Cell Biology Programme, CNIO, Madrid 28029, Spain.,

    Erwin F. Wagner

  2. Michele Petruzzelli is in the Department of Oncology, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.,

    Michele Petruzzelli

Authors
  1. Erwin F. Wagner
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  2. Michele Petruzzelli
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Correspondence to Erwin F. Wagner or Michele Petruzzelli.

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Wagner, E., Petruzzelli, M. A waste of insulin interference. Nature 521, 430–431 (2015). https://doi.org/10.1038/521430a

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