Every machine is made of parts. But, as the new structure of the HIV integrase enzyme in complex with viral DNA shows, one could not have predicted from the individual parts just how this machine works.
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Craigie, R. When four become one. Nature 464, 167–168 (2010). https://doi.org/10.1038/464167a
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DOI: https://doi.org/10.1038/464167a
