Abstract
IN the course of investigations of the vitamin A series1 three geometric isomers of all-trans vitamin A acid were recently synthesized by the method of Robeson et al.2. Although all-trans vitamin A acid maintains normal growth and skin appearance, it cannot replace vitamin A and its esters to the full extent in the rat3–8.
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References
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MAN, T., LEEUWEN, P. & ROBORGH, J. Growth Test and Liver Storage of All-trans Vitamin A Acid and Three of its Geometric Isomers with Chicks. Nature 201, 77–78 (1964). https://doi.org/10.1038/201077a0
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DOI: https://doi.org/10.1038/201077a0
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