Abstract
THE diabetic syndromes observed in experimental animals and in man are due to metabolic abnormalities induced directly or indirectly by insulin deficiency and to lesions which affect tissues other than the β-cells of the islets of Langerhans. It is difficult to attribute the pathological effects observed in these syndromes to specific lesions since the methods at present available do not render animals rapidly and reversibly insulin-deficient without provoking other complicating effects.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Moloney, P. J., and Coval, M., Biochem. J., 59, 179 (1955).
Wright, P. H., Biochem. J., 71, 633 (1959).
Wright, P. H., Lancet, ii, 621 (1957).
Feller, D. D., Strisower, E. H., and Chaikoff, I. L., J. Biol. Chem., 187, 571 (1950).
Stetten, De W., Welt, I. D., Ingel, D. J., and Morley, E. H., J. Biol. Chem., 192, 817 (1951).
Steels, R., Wall, J. S., de Bodo, R. C., and Altszuler, N., Amer. J. Physiol., 187, 15 (1956).
Bell, E. T., “Experimental Diabetes Mellitus” (Blackwell Scientific Publications, Oxford, 1948).
Danowski, T. S., “Diabetes Mellitus” (Williams and Wilkins, Baltimore, 1957).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
WRIGHT, P. Production of Acute Insulin Deficiency by Administration of Insulin Antiserum. Nature 183, 829–830 (1959). https://doi.org/10.1038/183829b0
Issue Date:
DOI: https://doi.org/10.1038/183829b0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
