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Post-Transplant Events

Ovarian recovery after stem cell transplantation

Bone Marrow Transplantation volume 41, pages 275–278 (2008)Cite this article

Abstract

Autologous or allogeneic SCT with conventional conditioning (chemotherapy with or without irradiation) has emerged as an effective and potentially curative therapy in patients with hematologic malignancies and in other selected solid tumors; however, several patients experience significant early and delayed side effects, including long-term endocrine imbalance and infertility. In spite of several reproductive recovery and pregnancy reports published in the oncology literature, review of medical literature reveals a paucity of comparable information in the SCT field. We report here four cases of ovarian recovery in patients who received hormonal replacement therapy after diagnosis of primary ovarian failure due to high-dose chemotherapy and SCT.

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Authors and Affiliations

  1. Department of Medicine, Moores University of California San Diego Cancer Center, University of California San Diego, San Diego, CA, USA

    J Liu, E D Ball & E Carrier

  2. Department of Public Health, San Diego State University, San Diego, CA, USA

    R Malhotra

  3. Centre for Cell Based Therapy and Bone Marrow Transplantation Unit, Medical School of Ribeirao Preto, University of Sao Paulo, Ribeirao Pieto, Brazil

    J Voltarelli, A B Stracieri, L Oliveira & B P Simoes

Authors
  1. J Liu
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  2. R Malhotra
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  3. J Voltarelli
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  4. A B Stracieri
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  5. L Oliveira
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  6. B P Simoes
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  7. E D Ball
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  8. E Carrier
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Correspondence to E Carrier.

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Liu, J., Malhotra, R., Voltarelli, J. et al. Ovarian recovery after stem cell transplantation. Bone Marrow Transplant 41, 275–278 (2008). https://doi.org/10.1038/sj.bmt.1705893

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  • DOI: https://doi.org/10.1038/sj.bmt.1705893

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