Testicular cancer articles within Nature Reviews Urology

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  • Case Study |

    Patients with carcinoma of unknown primary origin (CUP) pose a difficult diagnostic challenge, but a missed diagnosis of the primary tumor site is, unfortunately, a frequent occurrence. Musser and colleagues describe a patient with a large para-aortic mass that was initially diagnosed as CUP, but was subsequently identified as metastatic seminoma that showed remarkable spontaneous regression.

    • John E. Musser
    • , Christopher G. Przybycin
    •  & Paul Russo

  • News & Views |

    Patients diagnosed with clinical stage I (CS I) nonseminomatous germ cell tumors (NSGCT) have excellent survival. There are several therapies that contribute to this outcome and choosing among them can be challenging for both patient and physician. A decision tree analytical approach has been proposed, which incorporates quality of life outcomes and survival data to quantitatively determine the optimal approach for individual patients with CS I NSGCT.

    • Ornob P. Roy
    •  & Louis R. Kavoussi

  • Case Study |

    The authors describe a patient with a persistently elevated level of human chorionic gonadotropin (hCG) during chemotherapy for suspected low-risk, metastatic nonseminomatous germ cell tumor. His hCG level was found to have been falsely elevated owing to the presence of heterophile antibodies that interfered with the hCG immunoassay.

    • David J. Gallagher
    • , Jamie Riches
    •  & Dean F. Bajorin

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