Article
|
Open Access
Featured
-
-
Article
| Open AccessLarval microbiota primes the Drosophila adult gustatory response
How the larval environment influences the sensory characteristics of the future adult is largely unknown. Here, using Drosophila as a model, the authors show that the presence of certain bacterial species during the larval stage modify the gustatory capacities of the future adult flies.
- Martina Montanari
- , Gérard Manière
- & Julien Royet
-
Article
| Open AccessSatb2 neurons in the parabrachial nucleus mediate taste perception
The genetic identity of taste-responsive neurons has not been determined. The authors describe neurons in the gustatory region of the parabrachial nucleus that express the transcription factor Satb2, project to taste-associated regions, and modulate taste preferences.
- Brooke C. Jarvie
- , Jane Y. Chen
- & Richard D. Palmiter
-
Article
| Open AccessHeterogeneity in the Drosophila gustatory receptor complexes that detect aversive compounds
Taste sensilla are Drosophila sensory organs containing taste neurons, which have differential tuning for bitter compounds. Here, the authors systematically examine what combinations of gustatory receptor genes confer a specific taste response profile in different bitter taste neurons.
- Ha Yeon Sung
- , Yong Taek Jeong
- & Seok Jun Moon
-
Article
| Open AccessStructural basis for perception of diverse chemical substances by T1r taste receptors
Nutrients taste perception is mediated by T1r receptors that discriminate specific tastes among their wide diversity. Here the authors present crystal structures of the ligand-binding domains of the fish T1r2-T1r3 receptor, providing a structural framework for its ligand recognition.
- Nipawan Nuemket
- , Norihisa Yasui
- & Atsuko Yamashita
-
Article
| Open AccessFunctional dissociation in sweet taste receptor neurons between and within taste organs of Drosophila
Locating food sources is essential for the survival of animals. Here, the authors identify two functionally and anatomically distinct classes of sweet taste receptor neurons in Drosophila legs, involved in feeding initiation and sugar-dependent suppression of locomotion.
- Vladimiros Thoma
- , Stephan Knapek
- & Hiromu Tanimoto
-
Article
| Open AccessThe full repertoire of Drosophila gustatory receptors for detecting an aversive compound
It remains unclear whether any set of the 68 gustatory receptors expressed in Drosophilacomprise a cation channel that responds to an aversive chemical. Here the authors identify three gustatory receptors that are both necessary and sufficient to form a channel that confers sensitivity to a noxious tastant.
- Jaewon Shim
- , Youngseok Lee
- & Seok Jun Moon