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| Open AccessGlobal Similarity Method Based on a Two-tier Random Walk for the Prediction of microRNA–Disease Association
- Min Chen
- , Bo Liao
- & Zejun Li
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| Open AccessSpatiotemporal control of DNA-based chemical reaction network via electrochemical activation in microfluidics
- Ievgen Kurylo
- , Guillaume Gines
- & Alexis Vlandas
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| Open AccessDeviations of the immune cell landscape between healthy liver and hepatocellular carcinoma
- Nataliya Rohr-Udilova
- , Florian Klinglmüller
- & Michael Trauner
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| Open AccessMetabolomics and pathway analyses to characterize metabolic alterations in pregnant dairy cows on D 17 and D 45 after AI
- Y. S. Guo
- & J. Z. Tao
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| Open AccessCharacterization and non-parametric modeling of the developing serum proteome during infancy and early childhood
- Niina Lietzén
- , Lu Cheng
- & Riitta Lahesmaa
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Article
| Open AccessAsymmetric ommatidia count and behavioural lateralization in the ant Temnothorax albipennis
- Edmund R. Hunt
- , Ciara Dornan
- & Nigel R. Franks
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Article
| Open AccessHigh-resolution behavioral mapping of electric fishes in Amazonian habitats
- Manu S. Madhav
- , Ravikrishnan P. Jayakumar
- & Noah J. Cowan
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| Open AccessRule-based modelling provides an extendable framework for comparing candidate mechanisms underpinning clathrin polymerisation
- Anatoly Sorokin
- , Katharina F. Heil
- & Oksana Sorokina
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| Open AccessIMSindel: An accurate intermediate-size indel detection tool incorporating de novo assembly and gapped global-local alignment with split read analysis
- Daichi Shigemizu
- , Fuyuki Miya
- & Tatsuhiko Tsunoda
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| Open AccessA systems pharmacology-oriented discovery of a new therapeutic use of the TCM formula Liuweiwuling for liver failure
- Jia-bo Wang
- , He-rong Cui
- & Xiao-he Xiao
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Article
| Open AccessLow affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux
- Evert Bosdriesz
- , Meike T. Wortel
- & Bas Teusink
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Article
| Open AccessMetabolomics coupled with pathway analysis characterizes metabolic changes in response to BDE-3 induced reproductive toxicity in mice
- Ziheng Wei
- , Jing Xi
- & Xin Dong
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Article
| Open AccessAutomated brightfield morphometry of 3D organoid populations by OrganoSeg
- Michael A. Borten
- , Sameer S. Bajikar
- & Kevin A. Janes
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| Open AccessPersonalised drug repositioning for Clear Cell Renal Cell Carcinoma using gene expression
- Karel K. M. Koudijs
- , Anton G. T. Terwisscha van Scheltinga
- & Henk-Jan Guchelaar
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| Open AccessTopological estimation of signal flow in complex signaling networks
- Daewon Lee
- & Kwang-Hyun Cho
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Article
| Open AccessIdentification of the functional pathways altered by placental cell exposure to high glucose: lessons from the transcript and metabolite interactome
- C. H. Hulme
- , A. Stevens
- & J. E. Myers
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Article
| Open AccessA Poroelastic Model of a Fibrous-Porous Tissue Engineering Scaffold
- Daniel Yuan
- , Sarah M. Somers
- & Alexander A. Spector
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Article
| Open AccessParallel opsin switches in multiple cone types of the starry flounder retina: tuning visual pigment composition for a demersal life style
- Ilaria Savelli
- , Iñigo Novales Flamarique
- & John S. Taylor
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Article
| Open AccessCost-effective generation of precise label-free quantitative proteomes in high-throughput by microLC and data-independent acquisition
- Jakob Vowinckel
- , Aleksej Zelezniak
- & Markus Ralser
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Article
| Open AccessGlobal transcriptomic analysis suggests carbon dioxide as an environmental stressor in spaceflight: A systems biology GeneLab case study
- Afshin Beheshti
- , Egle Cekanaviciute
- & Sylvain V. Costes
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Article
| Open AccessA Mathematical Model of the Phosphoinositide Pathway
- Daniel V. Olivença
- , Inna Uliyakina
- & Francisco R. Pinto
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Article
| Open AccessEngineering Axl specific CAR and SynNotch receptor for cancer therapy
- Jang Hwan Cho
- , Atsushi Okuma
- & Wilson W. Wong
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Article
| Open AccessGene expression models based on a reference laboratory strain are poor predictors of Mycobacterium tuberculosis complex transcriptional diversity
- Álvaro Chiner-Oms
- , Fernando González-Candelas
- & Iñaki Comas
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Article
| Open AccessA metabolomics study of Qiliqiangxin in a rat model of heart failure: a reverse pharmacology approach
- Junzeng Fu
- , Liping Chang
- & Mei Wang
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Article
| Open AccessNetwork Motifs Capable of Decoding Transcription Factor Dynamics
- Zongmao Gao
- , Siheng Chen
- & Chao Tang
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| Open AccessHorizontal transfer of code fragments between protocells can explain the origins of the genetic code without vertical descent
- Tom Froese
- , Jorge I. Campos
- & Nathaniel Virgo
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Article
| Open AccessSystemic Homeostasis in Metabolome, Ionome, and Microbiome of Wild Yellowfin Goby in Estuarine Ecosystem
- Feifei Wei
- , Kenji Sakata
- & Jun Kikuchi
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Article
| Open AccessOptimization of ClpXP activity and protein synthesis in an E. coli extract-based cell-free expression system
- Xinying Shi
- , Ti Wu
- & Simpson Joseph
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Article
| Open AccessTranscription Factor Target Gene Network governs the Logical Abstraction Analysis of the Synthetic Circuit in Leishmaniasis
- Milsee Mol
- , Dipali Kosey
- & Shailza Singh
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Article
| Open AccessdynGENIE3: dynamical GENIE3 for the inference of gene networks from time series expression data
- Vân Anh Huynh-Thu
- & Pierre Geurts
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Article
| Open AccessEvolving Bacterial Fitness with an Expanded Genetic Code
- Drew S. Tack
- , Austin C. Cole
- & Andrew D. Ellington
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Article
| Open AccessAnalyzing the genes related to nicotine addiction or schizophrenia via a pathway and network based approach
- Ying Hu
- , Zhonghai Fang
- & Ju Wang
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Article
| Open AccessMolecular mechanisms of detection and discrimination of dynamic signals
- G. Antunes
- , A. C. Roque
- & F. M. Simoes-de-Souza
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Article
| Open AccessMethane utilization in Methylomicrobium alcaliphilum 20ZR: a systems approach
- Ilya R. Akberdin
- , Merlin Thompson
- & Marina G. Kalyuzhnaya
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Article
| Open AccessITGB1-dependent upregulation of Caveolin-1 switches TGFβ signalling from tumour-suppressive to oncogenic in prostate cancer
- Teijo Pellinen
- , Sami Blom
- & Miguel A. del Pozo
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Article
| Open AccessIn vitro RNA-seq-based toxicogenomics assessment shows reduced biological effect of tobacco heating products when compared to cigarette smoke
- Linsey E. Haswell
- , Sarah Corke
- & Emmanuel Minet
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Article
| Open AccessGenome-scale analysis of Methicillin-resistant Staphylococcus aureus USA300 reveals a tradeoff between pathogenesis and drug resistance
- Donghui Choe
- , Richard Szubin
- & Byung-Kwan Cho
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Article
| Open AccessUnderstanding non-linear effects from Hill-type dynamics with application to decoding of p53 signaling
- Xiaomin Shi
- & Jeffrey R. Reimers
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Article
| Open AccessThe transcriptional response to oxidative stress is part of, but not sufficient for, insulin resistance in adipocytes
- Rima Chaudhuri
- , James R. Krycer
- & David E. James
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Article
| Open AccessConsensus Clustering of temporal profiles for the identification of metabolic markers of pre-diabetes in childhood (EarlyBird 73)
- Mario Lauria
- , Maria Persico
- & François-Pierre Martin
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Article
| Open AccessNetwork of proteins, enzymes and genes linked to biomass degradation shared by Trichoderma species
- Maria Augusta Crivelente Horta
- , Jaire Alves Ferreira Filho
- & Anete Pereira de Souza
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Article
| Open AccessNoise-induced bistability in the fate of cancer phenotypic quasispecies: a bit-strings approach
- Josep Sardanyés
- & Tomás Alarcón
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Article
| Open AccessComputational trans-omics approach characterised methylomic and transcriptomic involvements and identified novel therapeutic targets for chemoresistance in gastrointestinal cancer stem cells
- Masamitsu Konno
- , Hidetoshi Matsui
- & Hideshi Ishii
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| Open AccessDynamic modelling of the mTOR signalling network reveals complex emergent behaviours conferred by DEPTOR
- Thawfeek M. Varusai
- & Lan K. Nguyen
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Article
| Open AccessSystems pharmacology analysis of synergy of TCM: an example using saffron formula
- Jianling Liu
- , Jingjing Liu
- & Yonghua Wang
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Article
| Open AccessComputational modelling of meiotic entry and commitment
- Tanvi Bhola
- , Orsolya Kapuy
- & P. K. Vinod
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Article
| Open AccessBlood plasma/IgG N-glycome biosignatures associated with major depressive disorder symptom severity and the antidepressant response
- Dong Ik Park
- , Jerko Štambuk
- & Christoph W. Turck
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Article
| Open AccessA Systematic Review and Meta-analysis of the Topical Administration of Fibrin Sealant in Total Hip Arthroplasty
- Zhihu Zhao
- , Xinlong Ma
- & Jianwei Lv
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Article
| Open AccessMultiple Cryptic Binding Sites are Necessary for Robust Fibronectin Assembly: An In Silico Study
- Christopher A. Lemmon
- & Seth H. Weinberg
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