Stem cells in the nervous system articles within Scientific Reports

Featured

• Article
  20 April 2024 | Open Access

  Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia

  • Zachary C. Rosenthal
  • , Daniel M. Fass
  •  & Stephen J. Haggarty

• Article
  08 February 2024 | Open Access

  Graft-derived neurons and bystander effects are maintained for six months after human iPSC-derived NESC transplantation in mice’s cerebella

  • Liliana S. Mendonça
  • , Daniel Henriques
  •  & Luís Pereira de Almeida

• Editorial
  23 October 2023 | Open Access

  Adult neurogenesis and aging mechanisms: a collection of insights

  Adult neurogenesis supports important brain functions, such as learning and memory, and its decrease during aging may contribute to the cognitive decline of the aged brain. This Collection provides insight into the role, regulation, and age-associated reduction of adult neurogenesis, by gathering studies investigating this process in different model systems, ages, and brain regions.

  • Giuseppe Lupo

• Article
  18 October 2023 | Open Access

  Use of transcranial low-intensity focused ultrasound for targeted delivery of stem cell-derived exosomes to the brain

  • J. Haroon
  • , K. Aboody
  •  & S. Jordan

• Article
  28 March 2023 | Open Access

  Transcriptomics of CD29⁺/CD44⁺ cells isolated from hPSC retinal organoids reveals a single cell population with retinal progenitor and Müller glia characteristics

  • Karen Eastlake
  • , Joshua Luis
  •  & G. Astrid Limb

• Article
  13 October 2022 | Open Access

  Combining NGN2 programming and dopaminergic patterning for a rapid and efficient generation of hiPSC-derived midbrain neurons

  • Razan Sheta
  • , Maxime Teixeira
  •  & Abid Oueslati

• Article
  15 July 2022 | Open Access

  Transcription-associated DNA DSBs activate p53 during hiPSC-based neurogenesis

  • Nadine Michel
  • , Heather M. Raimer Young
  •  & Michael J. McConnell

• Article
  01 June 2022 | Open Access

  Human cerebral spheroids undergo 4-aminopyridine-induced, activity associated changes in cellular composition and microrna expression

  • Thomas Parmentier
  • , Fiona M. K. James
  •  & Jonathan LaMarre

• Article
  13 April 2022 | Open Access

  Oscillatory calcium release and sustained store-operated oscillatory calcium signaling prevents differentiation of human oligodendrocyte progenitor cells

  • Richard A. Seidman
  • , Heba Khattab
  •  & Fraser J. Sim

• Article
  28 March 2022 | Open Access

  Rational design and synthesis of a novel BODIPY-based probe for selective imaging of tau tangles in human iPSC-derived cortical neurons

  • Alessandro Soloperto
  • , Deborah Quaglio
  •  & Alberto Boffi

• Article
  07 January 2022 | Open Access

  Identifying gene expression profiles associated with neurogenesis and inflammation in the human subependymal zone from development through aging

  • Mainá Bitar
  • , Christin Weissleder
  •  & Guy Barry

• Article
  25 March 2021 | Open Access

  The difficulty to model Huntington’s disease in vitro using striatal medium spiny neurons differentiated from human induced pluripotent stem cells

  • Kim Le Cann
  • , Alec Foerster
  •  & Angelika Lampert

• Article
  22 March 2021 | Open Access

  Intra-arterial transplantation of stem cells in large animals as a minimally-invasive strategy for the treatment of disseminated neurodegeneration

  • Izabela Malysz-Cymborska
  • , Dominika Golubczyk
  •  & Miroslaw Janowski

• Article
  14 December 2020 | Open Access

  Metabolomic analysis and mass spectrometry imaging after neonatal stroke and cell therapies in mouse brains

  • Emi Tanaka
  • , Yuko Ogawa
  •  & Masahiro Tsuji

• Article
  18 November 2020 | Open Access

  DCX⁺ neuronal progenitors contribute to new oligodendrocytes during remyelination in the hippocampus

  • Barbara Klein
  • , Heike Mrowetz
  •  & Ludwig Aigner

• Article
  31 July 2020 | Open Access

  Fabrication of homotypic neural ribbons as a multiplex platform optimized for spinal cord delivery

  • Zachary T. Olmsted
  • , Cinzia Stigliano
  •  & Janet L. Paluh

• Article
  23 July 2020 | Open Access

  Cranial irradiation at early postnatal age impairs stroke-induced neural stem/progenitor cell response in the adult brain

  • Susanne Neumann
  • , Michelle J. Porritt
  •  & H. Georg Kuhn

• Article
  20 April 2020 | Open Access

  Intraventricular Medium B Treatment Benefits an Ischemic Stroke Rodent Model via Enhancement of Neurogenesis and Anti-apoptosis

  • Yun-An Chen
  • , Yi-Chieh Tsai
  •  & Li-Kai Tsai

• Article
  23 December 2019 | Open Access

  Gender-specific effects of transthyretin on neural stem cell fate in the subventricular zone of the adult mouse

  • Pieter Vancamp
  • , Jean-David Gothié
  •  & Sylvie Remaud

• Article
  17 December 2019 | Open Access

  Tissue-type plasminogen activator-primed human iPSC-derived neural progenitor cells promote motor recovery after severe spinal cord injury

  • Yasuhiro Shiga
  • , Akina Shiga
  •  & Wendy M. Campana

• Article
  14 August 2019 | Open Access

  The systemic exercise-released chemokine lymphotactin/XCL1 modulates in vitro adult hippocampal precursor cell proliferation and neuronal differentiation

  • Odette Leiter
  • , Stefanie N. Bernas
  •  & Tara L. Walker

• Article
  03 July 2019 | Open Access

  FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes

  • Ekaterina Savchenko
  • , Gabriel N. Teku
  •  & Laurent Roybon

• Article
  21 June 2019 | Open Access

  A Simple Procedure for Creating Scalable Phenotypic Screening Assays in Human Neurons

  • BanuPriya Sridharan
  • , Christopher Hubbs
  •  & Timothy P. Spicer

• Article
  21 June 2019 | Open Access

  Development of glial restricted human neural stem cells for oligodendrocyte differentiation in vitro and in vivo

  • Sangita Biswas
  • , Seung Hyuk Chung
  •  & Wenbin Deng

• Article
  11 March 2019 | Open Access

  Early life stress delays hippocampal development and diminishes the adult stem cell pool in mice

  • Mary Youssef
  • , Piray Atsak
  •  & Alex Dranovsky

• Article
  18 December 2018 | Open Access

  Adult hippocampal neurogenesis occurs in the absence of Presenilin 1 and Presenilin 2

  • Jagroop Dhaliwal
  • , Timal S. Kannangara
  •  & Diane C. Lagace

• Article
  28 September 2018 | Open Access

  A dual role for the transcription factor Sp8 in postnatal neurogenesis

  • Elodie Gaborieau
  • , Anahi Hurtado-Chong
  •  & Olivier Raineteau

• Article
  19 September 2018 | Open Access

  N-Phenylquinazolin-2-amine Yhhu4952 as a novel promotor for oligodendrocyte differentiation and myelination

  • Xueli Yu
  • , Gang Cheng
  •  & Linyin Feng

• Article
  13 September 2018 | Open Access

  Groucho related gene 5 (GRG5) is involved in embryonic and neural stem cell state decisions

  • Konstantina Chanoumidou
  • , Christiana Hadjimichael
  •  & Androniki Kretsovali

• Article
  19 June 2018 | Open Access

  The Thrombin Receptor Restricts Subventricular Zone Neural Stem Cell Expansion and Differentiation

  • Chan-Il Choi
  • , Hyesook Yoon
  •  & Isobel A. Scarisbrick

• Article
  10 May 2018 | Open Access

  Effect of Bmi1 over-expression on gene expression in adult and embryonic murine neural stem cells

  • Mythily Ganapathi
  • , Nathan C. Boles
  •  & Randall H. Morse

• Article
  29 January 2018 | Open Access

  Foxj1 expressing ependymal cells do not contribute new cells to sites of injury or stroke in the mouse forebrain

  • Nagendran Muthusamy
  • , Andrew Brumm
  •  & H. Troy Ghashghaei

• Article
  18 January 2018 | Open Access

  The Proliferation Capacity of Cultured Neural Stem Cells Promoted by CSF Collected from SAH Patients Correlates to Clinical Outcome

  • Yun-An Chen
  • , Kuo-Chuan Wang
  •  & Li-Kai Tsai

• Article
  10 January 2018 | Open Access

  Olfactory memory is enhanced in mice exposed to extremely low-frequency electromagnetic fields via Wnt/β-catenin dependent modulation of subventricular zone neurogenesis

  • Alessia Mastrodonato
  • , Saviana Antonella Barbati
  •  & Claudio Grassi

• Article
  22 November 2017 | Open Access

  Encapsulation of primary dopaminergic neurons in a GDNF-loaded collagen hydrogel increases their survival, re-innervation and function after intra-striatal transplantation

  • Niamh Moriarty
  • , Abhay Pandit
  •  & Eilís Dowd

• Article
  08 November 2017 | Open Access

  Inter-individual variation in genes governing human hippocampal progenitor differentiation in vitro is associated with hippocampal volume in adulthood

  • Timothy R. Powell
  • , Tytus Murphy
  •  & Sandrine Thuret

• Article
  09 October 2017 | Open Access

  Short term changes in the proteome of human cerebral organoids induced by 5-MeO-DMT

  • Vanja Dakic
  • , Juliana Minardi Nascimento
  •  & Stevens K. Rehen

• Article
  29 September 2017 | Open Access

  Somatic Arc protein expression in hippocampal granule cells is increased in response to environmental change but independent of task-specific learning

  • J. P. Cleland
  • , E. F. Willis
  •  & J. Vukovic

• Article
  24 August 2017 | Open Access

  Cerium oxide nanoparticles inhibit differentiation of neural stem cells

  • Anda R. Gliga
  • , Karin Edoff
  •  & Bengt Fadeel

• Article
  24 July 2017 | Open Access

  Mechanically stable fibrin scaffolds promote viability and induce neurite outgrowth in neural aggregates derived from human induced pluripotent stem cells

  • Meghan Robinson
  • , Sarah Douglas
  •  & Stephanie Michelle Willerth

• Article
  20 July 2017 | Open Access

  Expansion of human midbrain floor plate progenitors from induced pluripotent stem cells increases dopaminergic neuron differentiation potential

  • Stefania Fedele
  • , Ginetta Collo
  •  & Verdon Taylor

• Article
  18 July 2017 | Open Access

  Graphene microfiber as a scaffold for regulation of neural stem cells differentiation

  • Weibo Guo
  • , Jichuan Qiu
  •  & Hong Liu

• Article
  07 July 2017 | Open Access

  Fluvoxamine stimulates oligodendrogenesis of cultured neural stem cells and attenuates inflammation and demyelination in an animal model of multiple sclerosis

  • Majid Ghareghani
  • , Kazem Zibara
  •  & Amir Ghanbari

• Article
  23 June 2017 | Open Access

  Mesenchymal stem cells secretome-induced axonal outgrowth is mediated by BDNF

  • Luís F. Martins
  • , Rui O. Costa
  •  & Ramiro D. Almeida

• Article
  16 March 2017 | Open Access

  Formyl peptide receptors promotes neural differentiation in mouse neural stem cells by ROS generation and regulation of PI3K-AKT signaling

  • Liang Zhang
  • , Guan Wang
  •  & Jianhua Zhao

• Article
  27 February 2017 | Open Access

  Inflammation-induced miRNA-155 inhibits self-renewal of neural stem cells via suppression of CCAAT/enhancer binding protein β (C/EBPβ) expression

  • Kayoko Obora
  • , Yuta Onodera
  •  & Kanji Fukuda

• Article
  24 January 2017 | Open Access

  Ependymal cell contribution to scar formation after spinal cord injury is minimal, local and dependent on direct ependymal injury

  • Yilong Ren
  • , Yan Ao
  •  & Michael V. Sofroniew

• Article
  16 January 2017 | Open Access

  Intraarterial route increases the risk of cerebral lesions after mesenchymal cell administration in animal model of ischemia

  • Bárbara Argibay
  • , Jesse Trekker
  •  & Francisco Campos

• Article
  07 December 2016 | Open Access

  The secretome of periodontal ligament stem cells from MS patients protects against EAE

  • Thangavelu Soundara Rajan
  • , Sabrina Giacoppo
  •  & Oriana Trubiani

• Article
  18 November 2016 | Open Access

  Quantitative proteomic analysis of age-related subventricular zone proteins associated with neurodegenerative disease

  • Xianli Wang
  • , Chuanming Dong
  •  & Jun Xu