Spine motility articles within Nature Communications

Featured

• Article
  26 March 2018 | Open Access

  Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction

  Direct visualization of microglia-mediated synapse pruning has been lacking. This study shows direct evidence of microglia-synapse interaction where microglia do not necessarily ‘eat’ post-synaptic structure but ‘nibble’ on pre-synaptic terminals, much akin to trogocytosis by lymphocytes.

  • Laetitia Weinhard
  • , Giulia di Bartolomei
  •  & Cornelius T. Gross

• Article
  07 March 2016 | Open Access

  CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits

  CSF-contacting neurons are known to project to locomotor CPGs although their relevance to active locomotion is unclear. Here, the authors show that these cells constitute a mechanosensory organ relying on PKD2L1 channels to detect spinal cord curvature and modulate locomotor frequency in freely moving animals.

  • Urs Lucas Böhm
  • , Andrew Prendergast
  •  & Claire Wyart