Short-term memory

  • Article
    | Open Access

    Identical physical inputs can evoke non-identical percepts. Here, the authors investigate the sources of such variability and find that rats and humans, trained to judge tactile vibration strength, express a robust sequential effect that could be modeled as the trial-by-trial incorporation of sensory history.

    • I. Hachen
    • , S. Reinartz
    •  & M. E. Diamond
  • Article
    | Open Access

    Epitranscriptomic modifications can regulate learning and memory. Here, the authors provide proteomic and functional analysis of N6-methyladenosine (m6A)-binding proteins in D. melanogaster and unveil behavioral and regulatory defects for m6A/Ythdf mutants.

    • Lijuan Kan
    • , Stanislav Ott
    •  & Eric C. Lai
  • Article
    | Open Access

    Synaptic plasticity ensures functionality during perturbations and enables memory formation. Here, the authors describe homeostatic functional and nano-modular active zone modifications for immediate and long-lasting enhancement of neurotransmitter release, and identify Unc13 as a presynaptic molecular target for homeostatic potentiation and learning.

    • Mathias A. Böhme
    • , Anthony W. McCarthy
    •  & Alexander M. Walter
  • Article
    | Open Access

    Memories formed around the same time are linked together by a shared temporal context. Here, the authors show that the ability to selectively retrieve distinct episodic memories formed close together in time is related to how quickly neural representations of temporal context change over time during encoding.

    • Mostafa M. El-Kalliny
    • , John H. Wittig Jr
    •  & Kareem A. Zaghloul
  • Article
    | Open Access

    Adaptation is thought to improve discrimination by pulling neural representations of similar stimuli farther apart. Here, the authors separately show that adaptation to a 3D shape class leads to better discrimination performance on similar shapes, and activity patterns diverge in object selective cortical areas.

    • Marcelo G. Mattar
    • , Maria Olkkonen
    •  & Geoffrey K. Aguirre
  • Article
    | Open Access

    Short-term memories (STM) can become long-term memories when occurring alongside novel experiences. Here, the authors investigate the neural mechanisms behind such 'behavioural tagging' and find STM neural populations are preferentially incorporated into the ensembles encoding novel experiences.

    • Masanori Nomoto
    • , Noriaki Ohkawa
    •  & Kaoru Inokuchi
  • Article
    | Open Access

    Lateral diffusion of receptors between synaptic and extrasynaptic sites is known to mediate plasticity. Hausrat et al. show that diffusion of α5-containing GABAAreceptors is controlled by phosphorylation of the extrasynaptic anchoring protein Radixin, and reveal a role for Radixin in learning and memory.

    • Torben J. Hausrat
    • , Mary Muhia
    •  & Matthias Kneussel