Proteomic analysis articles within Nature Reviews Genetics

Featured

• Review Article | 28 August 2020

  Genetics meets proteomics: perspectives for large population-based studies

  In this Review, Suhre, McCarthy and Schwenk describe how combining genetics with plasma proteomics is providing notable insights into human disease. As changes in the circulating proteome are often an intermediate molecular readout between a genetic variant and its organismal effect, proteomics can enable a deeper understanding of disease mechanisms, clinical biomarkers and therapeutic opportunities.

  • Karsten Suhre
  • , Mark I. McCarthy
  •  & Jochen M. Schwenk

• Review Article | 04 December 2012

  Next-generation proteomics: towards an integrative view of proteome dynamics

  Despite their complexity and dynamics, proteomes are starting to be comprehensively characterized; this has been made possible particularly by various technical advances in mass spectrometry. This Review highlights how proteomic studies are contributing to our understanding of various cellular processes in health and disease.

  • A. F. Maarten Altelaar
  • , Javier Munoz
  •  & Albert J. R. Heck