Proteolysis articles from across Nature Portfolio
Proteolysis is the enzymatic process by which proteins are degraded into their component polypeptide or amino acid parts. This generally occurs through protease-mediated hydrolysis of peptide bonds, but can also occur through non-enzymatic methods such as by action of mineral acids and heat.
Latest Research and Reviews
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Research
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DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation
Nature Communications 14, 1233 -
Research
| Open Access
A covalent BTK ternary complex compatible with targeted protein degradation
Nature Communications 14, 1189 -
UHRF1/UBE2L6/UBR4-mediated ubiquitination regulates EZH2 abundance and thereby melanocytic differentiation phenotypes in melanoma
Targeting HDAC3 to overcome the resistance to ATRA or arsenic in acute promyelocytic leukemia through ubiquitination and degradation of PML-RARα
Molecular sensing of mechano- and ligand-dependent adhesion GPCR dissociation
DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation
A covalent BTK ternary complex compatible with targeted protein degradation
Mechanisms controlling plant proteases and their substrates
C-degron mimicry confers E3 ligase selectivity
Running through the blocks
Mitochondrial PD-L1 modulates cancer immunotherapy
Life mimics art
Digoxin chronotherapy can modulate myocardial ischemia–reperfusion injury