Proteolysis articles within Nature Communications

Featured

• Article
  08 February 2011 | Open Access

  C-terminal UBA domains protect ubiquitin receptors by preventing initiation of protein degradation

  Rad23 and Dsk2 bind polyubiquitylated proteins and escort them to the proteasome for destruction. In this study, Heinenet al.investigate the molecular mechanisms that protect the C-terminal UBA domains of Rad23 and Dsk2 from proteasomal destruction.

  • Christian Heinen
  • , Klàra Ács
  •  & Nico P. Dantuma

• Article
  14 December 2010 | Open Access

  Systems-wide temporal proteomic profiling in glucose-starved Bacillus subtilis

  Identifying the transcripts and proteins that fluctuate in response to stimuli provides important information for understanding cell physiology. In this study, 52% of theBacillus subtilispredicted proteome is identified following glucose starvation, revealing further insight into protein dynamics at a global scale.

  • Andreas Otto
  • , Jörg Bernhardt
  •  & Dörte Becher