Probabilistic data networks

  • Article
    | Open Access

    Our understanding of the function of many transcripts is still incomplete, limiting the interpretability of transcriptomic data. Here the authors use consensus-independent component analysis, together with a guilt-by-association approach, to improve the prediction of gene function.

    • Carlos G. Urzúa-Traslaviña
    • , Vincent C. Leeuwenburgh
    •  & Rudolf S. N. Fehrmann
  • Article
    | Open Access

    Environments where antibiotics are used indiscriminately exhibit microbial communities that can represent hot-spots of resistance gene enrichment, which in turn could spread to humans. Here, the authors characterize how exposure to swine farms environment lead to temporal changes in the gut microbiome and resistome of healthy veterinary students.

    • Jian Sun
    • , Xiao-Ping Liao
    •  & Ya-Hong Liu
  • Article
    | Open Access

    Metabolic rewiring is a feature of many cancers. Here, the authors combine control theory and flux correlation analysis to study the transition of healthy metabolic networks to cancer states, and find that cancer metabolism is characterized by more streamlined flux distributions.

    • Jean-Marc Schwartz
    • , Hiroaki Otokuni
    •  & Jose C. Nacher
  • Article
    | Open Access

    When two spatially separated parties flip a coin, it is impossible to choose between two alternatives in an unbiased manner. This study presents a quantum coin-flipping protocol that overcomes this problem and ensures a dishonest party cannot bias the outcome completely.

    • Guido Berlín
    • , Gilles Brassard
    •  & Wolfgang Tittel