Pregnancy outcome articles within Nature Reviews Cardiology

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  • Review Article |

    The numerous physiological changes that occur during pregnancy can affect the pharmacokinetics of drugs that a woman is receiving, often warranting an alteration in dosage. The well-being of the fetus is a major concern among pregnant women who require treatment for their heart disease. In this Review, Pieper provides an overview of the pharmacokinetic changes in drugs for cardiovascular disease during pregnancy, and how these might affect the fetus.

    • Petronella G. Pieper

  • News & Views |

    A study by Li and coworkers demonstrates that antihypertensive-drug use and untreated hypertension in pregnancy increase the risk of congenital malformations. Supported by the results of meta-analysis, this study heralds a major shift in our understanding of the fetal risks of hypertension and the medications used to treat this condition.

    • Gideon Koren

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