Comment
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Open Access
Featured
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Comment
| Open AccessOne Health approach at the heart of the French Committee for monitoring and anticipating health risks
Following the COVID-19 pandemic, the French government established a committee for monitoring and anticipating health risks. In this Comment, the authors describe the One Health approach taken by the committee, and outline its aims, composition, and initial actions.
- Thierry Lefrançois
- , Bruno Lina
- & Brigitte Autran
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Comment
| Open AccessEngineered and natural gene drives: mechanistically the same, yet not same in kind
We propose the use of the terms natural gene drive (NGD) and engineered gene drive (EGD) arguing against James et al.
1 , who think both should be included within the term “gene drive”, based on their mechanistic similarities.- Raul F. Medina
- & Jennifer Kuzma
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Comment
| Open AccessZoonotic malaria requires new policy approaches to malaria elimination
WHO guidelines for classification of malaria elimination in a country require that the risk of human infection from zoonotic, as well as nonzoonotic, malaria parasites is negligible. In this Comment, the authors discuss the implications of this policy for countries, such as Malaysia, with no recent reported nonzoonotic cases but ongoing zoonotic transmission.
- Kimberly M. Fornace
- , Chris J. Drakeley
- & Kamruddin Ahmed
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Comment
| Open AccessEthical considerations for researchers developing and testing minimal-risk devices
This comment explores ethical aspects in developing and testing minimal-risk devices, such as wearables and biomedical sensors. Authors outline the process of independent review, emphasizing the different levels of review depending on the research design and risk level. They also share examples of practical scenarios, highlighting key ethical considerations.
- Anna Wexler
- & Emily Largent
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Comment
| Open AccessA gene drive is a gene drive: the debate over lumping or splitting definitions
We address a controversy over use of the term “gene drive” to include both natural and synthetic genetic elements that promote their own transmission within a population, arguing that this broad definition is both practical and has advantages for risk analysis.
- Stephanie L. James
- , David A. O’Brochta
- & Omar S. Akbari
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Article
| Open AccessRegional clozapine, ECT and lithium usage inversely associated with excess suicide rates in male adolescents
There are conflicting results on the effectiveness of pharmacologic interventions for suicide prevention in adolescence. Here, the authors show, in a retrospective registry study from Sweden during 2016–2020, that regional utilization rates of clozapine, electroconvulsive therapy and lithium in 15–19-year-olds were associated with lower excess suicide death rates in male adolescents
- Adrian E. Desai Boström
- , Peter Andersson
- & Jussi Jokinen
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Article
| Open AccessA scoping review of the impacts of COVID-19 physical distancing measures on vulnerable population groups
Physical distancing measures introduced to control the spread of COVID-19 had socio-economic trade-offs that may have particularly impacted vulnerable population groups. Here, the authors perform a scoping review and summarise the impacts on different vulnerable groups described in 265 studies.
- Lili Li
- , Araz Taeihagh
- & Si Ying Tan
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Article
| Open AccessGlobal disparities in SARS-CoV-2 genomic surveillance
In this study, the authors provide a global overview of SARS-CoV-2 genome sequencing, and estimate the proportion of cases sequenced and time to genome upload. They identify disparities and highlight the need to strengthen surveillance in lower and middle income countries.
- Anderson F. Brito
- , Elizaveta Semenova
- & Nuno R. Faria
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Article
| Open AccessEconomic interests cloud hazard reductions in the European regulation of substances of very high concern
The most important variable explaining the regulation of chemical substances of very high concern in the European REACH regulation is not how dangerous a chemical is but the fact that it is not produced nor imported into the European Economic Area.
- Jessica Coria
- , Erik Kristiansson
- & Mikael Gustavsson
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Comment
| Open AccessA global forum on synthetic biology: the need for international engagement
A Global Forum on Synthetic Biology is needed to engage policymakers with practitioners across borders at the highest level. The international community needs a global confidence-building measure focused on discussing policy futures for the age of engineering biology.
- Thomas A. Dixon
- , Paul S. Freemont
- & Isak S. Pretorius
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Comment
| Open AccessCommunity voices: Achieving real diversity in STEM requires the ability to transform institutions
Resilience is often invoked to address systemic marginalization (e.g. racism) in academia but inadvertently maintains harmful systems. We argue that the ability to transform systems, as opposed to persevering within them, must be prioritized to make real, lasting change.
- Jory C. Lerback
- , Monique M. Holt
- & Stephanie Alvarez
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Comment
| Open AccessCommunity voices: the importance of diverse networks in academic mentoring
Mentor relationships are crucial to retention, success, and wellbeing of women and underrepresented minority scientists in academia. A network of diverse mentors may support achieving long-term career goals, advancement, and retention of both mentors and mentees, thus enhancing diversity, equity, and inclusion initiatives.
- Rocío Deanna
- , Bethann Garramon Merkle
- & Gabriela Auge
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Comment
| Open AccessMultilateral benefit-sharing from digital sequence information will support both science and biodiversity conservation
Ensuring international benefit-sharing from sequence data without jeopardising open sharing is a major obstacle for the Convention on Biological Diversity and other UN negotiations. Here, the authors propose a solution to address the concerns of both developing countries and life scientists.
- Amber Hartman Scholz
- , Jens Freitag
- & Jörg Overmann
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Perspective
| Open AccessAn actionable anti-racism plan for geoscience organizations
Racism thrives in geoscience. We present an antiracism plan to support the recruitment, retention and success of Black, Indigenous, and other people of color in geoscience. Our action plan can be adapted by any organization to remove barriers to participation for all marginalized geoscientists.
- Hendratta N. Ali
- , Sarah L. Sheffield
- & Blair Schneider
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Perspective
| Open AccessThe biosecurity benefits of genetic engineering attribution
A key security challenge with biosecurity threats is determining the responsible actor. In this Perspective, the authors review recent developments in using genetic sequence to assign a lab-of-origin and the potential protection it provides against misuse of synthetic biology.
- Gregory Lewis
- , Jacob L. Jordan
- & Thomas V. Inglesby
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Perspective
| Open AccessMicroplastic regulation should be more precise to incentivize both innovation and environmental safety
Plastic pollution is recognized as a global threat, but policy hurdles and a lack of effective plastic substitutes contribute to the problem. In this Perspective, the authors argue that an effective and sustainable path forward must rely on key restrictions and regulations optimized for impact and efficacy.
- Denise M. Mitrano
- & Wendel Wohlleben
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Comment
| Open AccessHigh-altitude populations need special considerations for COVID-19
- Arnar Breevoort
- , Giovanni A. Carosso
- & Mohammed A. Mostajo-Radji
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Comment
| Open AccessOpportunities for big data in conservation and sustainability
Big data reveals new, stark pictures of the state of our environments. It also reveals ‘bright spots’ amongst the broad pattern of decline and—crucially—the key conditions for these cases. Big data analyses could benefit the planet if tightly coupled with ongoing sustainability efforts.
- Rebecca K. Runting
- , Stuart Phinn
- & James E. M. Watson
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Comment
| Open AccessThe sharing economy promotes sustainable societies
Sharing activities are under wide debate regarding the environmental impacts. Here the authors reviewed their benefits and problems and suggested that a simultaneous improvement of both ecological and economic efficiency is necessary to achieve the Sustainable Development Goals (SDGs).
- Zhifu Mi
- & D’Maris Coffman
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Article
| Open AccessPractice and perspectives in the validation of resource management models
Credibility of long-term projection in quantitative models is continuously under debate and they rely on validation to prove projection accuracy. Here the authors investigated the views on the validation approaches and they show that empirical data plays an important role in the validation practice in all main areas of sustainability science.
- Sibel Eker
- , Elena Rovenskaya
- & Simon Langan
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Comment
| Open AccessBuilding optimism at the environmental science-policy-practice interface through the study of bright spots
- Christopher Cvitanovic
- & Alistair J. Hobday
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Perspective
| Open AccessA framework for enhancing ethical genomic research with Indigenous communities
Indigenous peoples are still underrepresented in genetic research. Here, the authors propose an ethical framework consisting of six major principles that encourages researchers and Indigenous communities to build strong and equal partnerships to increase trust, engagement and diversity in genomic studies.
- Katrina G. Claw
- , Matthew Z. Anderson
- & Joseph M. Yracheta
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Article
| Open AccessAssessment of the impact of shared brain imaging data on the scientific literature
Data sharing is recognized as a way to promote scientific collaboration and reproducibility, but some are concerned over whether research based on shared data can achieve high impact. Here, the authors show that neuroimaging papers using shared data are no less likely to appear in top-ranked journals.
- Michael P. Milham
- , R. Cameron Craddock
- & Arno Klein
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