Parathyroid hormone articles within Nature Communications

Featured

• Article
  31 May 2023 | Open Access

  An injectable liposome-anchored teriparatide incorporated gallic acid-grafted gelatin hydrogel for osteoarthritis treatment

  Osteoarthritis is a common disease that causes pain and difficulty moving joints. Here the authors present an injectable gelatin-based hydrogel that slowly releases teriparatide drug to avoid frequent injections, offering a potential solution for patients with osteoarthritis.

  • Guoqing Li
  • , Su Liu
  •  & Hui Zeng

• Article
  22 March 2019 | Open Access

  TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone

  Parathyroid hormone (PTH) is used to treat osteoporosis, but its therapeutic mechanism remains unclear. Here, the authors show that Tgif1 is a PTH target gene, and that its deletion impairs the function of osteoblasts and PTH-induced bone formation in mice.

  • Hiroaki Saito
  • , Andreas Gasser
  •  & Eric Hesse

• Article
  12 April 2016 | Open Access

  Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation

  How the parathyroid hormone-related protein receptor (PPR) and its ligand act in root formation and tooth eruption is unclear. Here, the authors identify osterix-expressing dental mesenchymal cells as progenitors for root formation and that PPR signalling mediates their differentiation and tooth eruption.

  • Wanida Ono
  • , Naoko Sakagami
  •  & Henry M. Kronenberg