Nanopores articles from across Nature Portfolio

Nanopores are nanoscale pores in electrically insulating materials used to study the physical properties of biomolecules by measuring changes in current as individual molecules transit. Nanopore arrays are constructed from channel proteins in lipid membranes or from pores patterned in synthetic materials, and can sequence DNA or characterize protein folding.

Latest Research and Reviews

News and Comment

  • Comments & Opinion |

    Nanopore direct RNA sequencing (DRS) reads continuous native RNA strands. Early adopters have used this technology to document nucleotide modifications and 3′ polyadenosine tails on RNA strands without added chemistry steps. Individual strands ranging in length from 70 to 26,000 nucleotides have been sequenced. In our opinion, broader acceptance of nanopore DRS by molecular biologists and cell biologists will be accelerated by higher basecall accuracy and lower RNA input requirements.

    • Miten Jain
    • , Robin Abu-Shumays
    •  & Mark Akeson
    Nature Methods 19, 1160-1164
  • News & Views |

    Anion-selective covalent organic framework (COF) membranes fabricated using laminar assembly and interfacial polymerization exhibit enhanced potential for osmotic power generation.

    • Laxmicharan Samineni
    •  & Manish Kumar
    Nature Nanotechnology 17, 564-566