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| Open AccessAbsence of cytoglobin promotes multiple organ abnormalities in aged mice
- Le Thi Thanh Thuy
- , Tuong Thi Van Thuy
- & Norifumi Kawada
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| Open AccessEvaluation of energy metabolism and calcium homeostasis in cells affected by Shwachman-Diamond syndrome
- Silvia Ravera
- , Carlo Dufour
- & Enrico Cappelli
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| Open AccessNotch signaling indirectly promotes chondrocyte hypertrophy via regulation of BMP signaling and cell cycle arrest
- Xifu Shang
- , Jinwu Wang
- & Yufeng Dong
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| Open AccessInfluence of DNA extraction methods on relative telomere length measurements and its impact on epidemiological studies
- Julia Raschenberger
- , Claudia Lamina
- & Florian Kronenberg
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| Open AccessElucidation of molecular and functional heterogeneity through differential expression network analyses of discrete tumor subsets
- Rutika R. Naik
- , Nilesh L. Gardi
- & Sharmila A. Bapat
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| Open AccessTriple-acting Lytic Enzyme Treatment of Drug-Resistant and Intracellular Staphylococcus aureus
- Stephen C. Becker
- , Dwayne R. Roach
- & David M. Donovan
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| Open AccessA life course approach to explore the biological embedding of socioeconomic position and social mobility through circulating inflammatory markers
- Raphaële Castagné
- , Cyrille Delpierre
- & Marc Chadeau-Hyam
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| Open AccessHedgehog signaling activation induces stem cell proliferation and hormone release in the adult pituitary gland
- Joanna Pyczek
- , Rolf Buslei
- & Anja Uhmann
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| Open AccessA somatic reference standard for cancer genome sequencing
- David W. Craig
- , Sara Nasser
- & Winnie S. Liang
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| Open AccessOrthogonal NGS for High Throughput Clinical Diagnostics
- Niru Chennagiri
- , Eric J. White
- & John F. Thompson
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| Open AccessCharacterization of the 5′-flanking region of the human DNA helicase B (HELB) gene and its response to trans-Resveratrol
- Fumiaki Uchiumi
- , Jun Arakawa
- & Sei-ichi Tanuma
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| Open AccessInter-polysomal coupling of termination and initiation during translation in eukaryotic cell-free system
- Evgeny A. Sogorin
- , Sultan Ch. Agalarov
- & Alexander S. Spirin
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| Open AccessRe-polarizing Myeloid-derived Suppressor Cells (MDSCs) with Cationic Polymers for Cancer Immunotherapy
- Wei He
- , Pei Liang
- & Junfeng Zhang
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| Open AccessGrowth factor restriction impedes progression of wound healing following cataract surgery: identification of VEGF as a putative therapeutic target
- Julie A. Eldred
- , Matthew McDonald
- & I. Michael Wormstone
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Article
| Open AccessCombined Population Dynamics and Entropy Modelling Supports Patient Stratification in Chronic Myeloid Leukemia
- Marc Brehme
- , Steffen Koschmieder
- & Andreas Schuppert
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| Open AccessMicropapillary: A component more likely to harbour heterogeneous EGFR mutations in lung adenocarcinomas
- Yi-Ran Cai
- , Yu-Jie Dong
- & Ying-Li Zhao
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| Open AccessMolecular surveillance of nasopharyngeal carriage of Streptococcus pneumoniae in children vaccinated with conjugated polysaccharide pneumococcal vaccines
- Anne L. Wyllie
- , Alienke J. Wijmenga-Monsuur
- & Krzysztof Trzciński
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| Open AccessSomatic Mutations and Genetic Variants of NOTCH1 in Head and Neck Squamous Cell Carcinoma Occurrence and Development
- Yu-Fan Liu
- , Shang-Lun Chiang
- & Ying-Chin Ko
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| Open AccessBirth mode-dependent association between pre-pregnancy maternal weight status and the neonatal intestinal microbiome
- Noel T. Mueller
- , Hakdong Shin
- & Maria Gloria Dominguez-Bello
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Article
| Open AccessImbalance in chemical space: How to facilitate the identification of protein-protein interaction inhibitors
- Mélaine A. Kuenemann
- , Céline M. Labbé
- & Olivier Sperandio
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| Open AccessEplerenone restores 24-h blood pressure circadian rhythm and reduces advanced glycation end-products in rhesus macaques with spontaneous hypertensive metabolic syndrome
- Yan Zhang
- , Wen Zheng
- & Xiuqin Zhang
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| Open AccessSuppressive effect of exogenous carbon monoxide on endotoxin-stimulated platelet over-activation via the glycoprotein-mediated PI3K-Akt-GSK3β pathway
- Dadong Liu
- , Xu Wang
- & Bingwei Sun
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| Open AccessTranscriptome profile of the early stages of breast cancer tumoral spheroids
- Rosario Pacheco-Marín
- , Jorge Melendez-Zajgla
- & Vilma Maldonado
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| Open AccessQuantification of HER2 heterogeneity in breast cancer–implications for identification of sub-dominant clones for personalised treatment
- Niamh E. Buckley
- , Claire Forde
- & Manuel Salto-Tellez
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| Open AccessMicheliolide inhibits LPS-induced inflammatory response and protects mice from LPS challenge
- Xiangyang Qin
- , Xinru Jiang
- & Yuejuan Zheng
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| Open AccessSingle-molecule analysis of DNA replication reveals novel features in the divergent eukaryotes Leishmania and Trypanosoma brucei versus mammalian cells
- Slavica Stanojcic
- , Lauriane Sollelis
- & Yvon Sterkers
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| Open AccessNOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis
- Mari H. Tervaniemi
- , Shintaro Katayama
- & Outi Elomaa
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Article
| Open AccessSustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways
- Julia Barbara Kral
- , Mario Kuttke
- & Gernot Schabbauer
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Article
| Open AccessUsing AAV vectors expressing the β2-adrenoceptor or associated Gα proteins to modulate skeletal muscle mass and muscle fibre size
- Adam Hagg
- , Timothy D. Colgan
- & Paul Gregorevic
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| Open AccessOverexpression of microRNA-634 suppresses survival and matrix synthesis of human osteoarthritis chondrocytes by targeting PIK3R1
- Xu Cui
- , Shaojie Wang
- & Chun Xia
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Article
| Open AccessEffects of Systemically Administered Hydrocortisone on the Human Immunome
- Matthew J. Olnes
- , Yuri Kotliarov
- & Neal S. Young
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Article
| Open AccessSecreted APE1/Ref-1 inhibits TNF-α-stimulated endothelial inflammation via thiol-disulfide exchange in TNF receptor
- Myoung Soo Park
- , Sunga Choi
- & Byeong Hwa Jeon
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Article
| Open AccessComplement factor H binding of monomeric C-reactive protein downregulates proinflammatory activity and is impaired with at risk polymorphic CFH variants
- Blanca Molins
- , Pablo Fuentes-Prior
- & Andrew D. Dick
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| Open AccessAn integrative approach to investigate the respective roles of single-nucleotide variants and copy-number variants in Attention-Deficit/Hyperactivity Disorder
- Leandro de Araújo Lima
- , Ana Cecília Feio-dos-Santos
- & Helena Brentani
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| Open AccessMacrophage Migration Inhibitory Factor (MIF) Deficiency Exacerbates Aging-Induced Cardiac Remodeling and Dysfunction Despite Improved Inflammation: Role of Autophagy Regulation
- Xihui Xu
- , Jiaojiao Pang
- & Jun Ren
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| Open AccessIntranasal Delivery of Recombinant AAV Containing BDNF Fused with HA2TAT: a Potential Promising Therapy Strategy for Major Depressive Disorder
- Xian-cang Ma
- , Peng Liu
- & Cheng-ge Gao
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| Open AccessToll-like Receptor 9 Can be Activated by Endogenous Mitochondrial DNA to Induce Podocyte Apoptosis
- Wenduona Bao
- , Hong Xia
- & Shaolin Shi
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| Open AccessThe Lipid Bilayer Provides a Site for Cortisone Crystallization at High Cortisone Concentrations
- Richard J. Alsop
- , Adree Khondker
- & Maikel C. Rheinstädter
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| Open AccessMiR-590-5p Inhibits Oxidized- LDL Induced Angiogenesis by Targeting LOX-1
- Yao Dai
- , Zhigao Zhang
- & Jun Li
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| Open AccessThe current use and attitudes towards tumor genome sequencing in breast cancer
- I. Gingras
- , A. Sonnenblick
- & H. A. Azim Jr
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| Open AccessMembrane type 1-matrix metalloproteinase induces epithelial-to-mesenchymal transition in esophageal squamous cell carcinoma: Observations from clinical and in vitro analyses
- Lijuan Pang
- , Qiuxiang Li
- & Feng Li
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| Open AccessDifferential expression of p38 MAPK α, β, γ, δ isoforms in nucleus pulposus modulates macrophage polarization in intervertebral disc degeneration
- Chen Yang
- , Peng Cao
- & Wen Yuan
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| Open AccessIdentifying protective Streptococcus pyogenes vaccine antigens recognized by both B and T cells in human adults and children
- Rasmus Mortensen
- , Thomas Nørrelykke Nissen
- & Jes Dietrich
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| Open AccessReceptor-targeted liposome-peptide-siRNA nanoparticles represent an efficient delivery system for MRTF silencing in conjunctival fibrosis
- Cynthia Yu-Wai-Man
- , Aristides D. Tagalakis
- & Peng T. Khaw
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| Open AccessAntithrombotic and antiplatelet activities of small-molecule alkaloids from Scolopendra subspinipes mutilans
- Wonhwa Lee
- , JungIn Lee
- & Jong-Sup Bae
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| Open AccessHeme oxygenase-1 induction attenuates imiquimod-induced psoriasiform inflammation by negative regulation of Stat3 signaling
- Bin Zhang
- , Sijing Xie
- & Hongwei Wang
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| Open AccessAmelioration of intracellular stress and reduction of neural tube defects in embryos of diabetic mice by phytochemical quercetin
- Lixue Cao
- , Chengyu Tan
- & Zhiyong Zhao
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Article
| Open AccessCardioprotective effects of Notoginsenoside R1 against ischemia/reperfusion injuries by regulating oxidative stress- and endoplasmic reticulum stress- related signaling pathways
- Yingli Yu
- , Guibo Sun
- & Xiaobo Sun
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| Open AccessAngiotensin-converting enzyme 2/angiotensin-(1–7)/Mas axis activates Akt signaling to ameliorate hepatic steatosis
- Xi Cao
- , Fangyuan Yang
- & Jin-Kui Yang