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| Open AccessMechanistic insight into the norepinephrine-induced fibrosis in systemic sclerosis
- Akihito Uehara
- , Sei-ichiro Motegi
- & Osamu Ishikawa
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| Open AccessEffects of Methotrexate in a Rabbit Model of In-Stent Neoatherosclerosis: An Optical Coherence Tomography Study
- Ruoxi Zhang
- , Shuyuan Chen
- & Jingbo Hou
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| Open AccessAdenovirus-mediated expression of orphan nuclear receptor NR4A2 targeting hepatic stellate cell attenuates liver fibrosis in rats
- Pengguo Chen
- , Jie Li
- & Cheng Guo
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| Open AccessThe use of cellular thermal shift assay (CETSA) to study Crizotinib resistance in ALK-expressing human cancers
- Abdulraheem Alshareef
- , Hai-Feng Zhang
- & Raymond Lai
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| Open AccessEntinostat up-regulates the CAMP gene encoding LL-37 via activation of STAT3 and HIF-1α transcription factors
- Erica Miraglia
- , Frank Nylén
- & Peter Bergman
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| Open AccessGenome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion
- Elisabet Einarsdottir
- , Lena Hafrén
- & Petri S. Mattila
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| Open AccessComplex inheritance in Pulmonary Arterial Hypertension patients with several mutations
- Guillermo Pousada
- , Adolfo Baloira
- & Diana Valverde
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| Open AccessIdentification of Viruses in Cases of Pediatric Acute Encephalitis and Encephalopathy Using Next-Generation Sequencing
- Jun-ichi Kawada
- , Yusuke Okuno
- & Yoshinori Ito
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| Open AccessAn integrative study identifies KCNC2 as a novel predisposing factor for childhood obesity and the risk of diabetes in the Korean population
- Joo-Yeon Hwang
- , Hyo Jung Lee
- & Hye-Ja Lee
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| Open AccessCharacterization of a knock-in mouse model of the homozygous p.V37I variant in Gjb2
- Ying Chen
- , Lingxiang Hu
- & Hao Wu
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| Open AccessThe analysis of heterotaxy patients reveals new loss-of-function variants of GRK5
- Davor Lessel
- , Tariq Muhammad
- & Melanie Philipp
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| Open AccessMolecular organization, localization and orientation of antifungal antibiotic amphotericin B in a single lipid bilayer
- Wojciech Grudzinski
- , Joanna Sagan
- & Wieslaw I. Gruszecki
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| Open AccessProtease-activated receptor-1 deficiency protects against streptozotocin-induced diabetic nephropathy in mice
- Maaike Waasdorp
- , JanWillem Duitman
- & C. Arnold Spek
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| Open AccessMutation screening of GRIN2B in schizophrenia and autism spectrum disorder in a Japanese population
- Yuto Takasaki
- , Takayoshi Koide
- & Norio Ozaki
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| Open AccessTracing Mycobacterium tuberculosis transmission by whole genome sequencing in a high incidence setting: a retrospective population-based study in East Greenland
- K. Bjorn-Mortensen
- , B. Soborg
- & T. A. Kohl
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| Open AccessPaeoniflorin Potentiates the Inhibitory Effects of Erlotinib in Pancreatic Cancer Cell Lines by Reducing ErbB3 Phosphorylation
- Jian Hao
- , Xue Yang
- & Xiong-zhi Wu
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| Open AccessTherapeutically targeting mitochondrial redox signalling alleviates endothelial dysfunction in preeclampsia
- Cathal McCarthy
- & Louise C. Kenny
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| Open AccessUbiquitin carboxyl-terminal hydrolase-L5 promotes TGFβ-1 signaling by de-ubiquitinating and stabilizing Smad2/Smad3 in pulmonary fibrosis
- Ling Nan
- , Anastasia M. Jacko
- & Yutong Zhao
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Article
| Open AccessFunctional changes in Becker muscular dystrophy: implications for clinical trials in dystrophinopathies
- Luca Bello
- , Paola Campadello
- & Elena Pegoraro
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| Open AccessAcetylated α-Tubulin Regulated by N-Acetyl-Seryl-Aspartyl-Lysyl-Proline(Ac-SDKP) Exerts the Anti-fibrotic Effect in Rat Lung Fibrosis Induced by Silica
- Wang Xiaojun
- , Liu Yan
- & Yang Fang
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Article
| Open AccessMitochondrial role in adaptive response to stress conditions in preeclampsia
- Polina A. Vishnyakova
- , Maria A. Volodina
- & Gennady T. Sukhikh
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| Open AccessA-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma
- Hiroyuki Kanzaki
- , Fumiaki Shinohara
- & Yoshiki Nakamura
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| Open AccessFactors regulating capillary remodeling in a reversible model of inflammatory corneal angiogenesis
- Anthony Mukwaya
- , Beatrice Peebo
- & Neil Lagali
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Article
| Open AccessProtective effect of salidroside against bone loss via hypoxia-inducible factor-1α pathway-induced angiogenesis
- Ling Li
- , Ye Qu
- & Ling Zhi Li
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Article
| Open AccessAAV8-Mediated Angiotensin-Converting Enzyme 2 Gene Delivery Prevents Experimental Autoimmune Uveitis by Regulating MAPK, NF-κB and STAT3 Pathways
- Yiguo Qiu
- , Lifei Tao
- & Bo Lei
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| Open AccessTGF-β1 promotes scar fibroblasts proliferation and transdifferentiation via up-regulating MicroRNA-21
- Ying Liu
- , Yue Li
- & Zhibo Xiao
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| Open AccessNoncoding RNA-regulated gain-of-function of STOX2 in Finnish pre-eclamptic families
- Cees BM Oudejans
- , Ankie Poutsma
- & Marie van Dijk
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| Open AccessTranscriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs
- Ying Qu
- , Bo Zhou
- & Xiaojiang Cui
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| Open AccessMonitoring Tumor Hypoxia Using 18F-FMISO PET and Pharmacokinetics Modeling after Photodynamic Therapy
- Xiao Tong
- , Avinash Srivatsan
- & Xiaoyuan Chen
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Article
| Open AccessMolecular circadian rhythm shift due to bright light exposure before bedtime is related to subthreshold bipolarity
- Chul-Hyun Cho
- , Joung-Ho Moon
- & Heon-Jeong Lee
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| Open AccessAnalysis of Post-Traumatic Brain Injury Gene Expression Signature Reveals Tubulins, Nfe2l2, Nfkb, Cd44 and S100a4 as Treatment Targets
- Anssi Lipponen
- , Jussi Paananen
- & Asla Pitkänen
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| Open AccessEnzyme overexpression – an exercise toward understanding regulation of heparan sulfate biosynthesis
- Jianping Fang
- , Tianyi Song
- & Jin-Ping Li
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| Open AccessStratification of responders towards eculizumab using a structural epitope mapping strategy
- Anna-Luisa Volk
- , Francis Jingxin Hu
- & Johan Rockberg
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| Open AccessThe caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function
- Vânia L. Batalha
- , Diana G. Ferreira
- & Luísa V. Lopes
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| Open AccessmiRNA profiles in livers with different mass deficits after partial hepatectomy and miR-106b~25 cluster accelerating hepatocyte proliferation in rats
- Xiao Xu
- , Zhikun Liu
- & Shusen Zheng
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| Open AccessMenopause-induced uterine epithelium atrophy results from arachidonic acid/prostaglandin E2 axis inhibition-mediated autophagic cell death
- Shengtao Zhou
- , Linjie Zhao
- & Xia Zhao
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| Open AccessIn Vivo Imaging of Retinal Hypoxia in a Model of Oxygen-Induced Retinopathy
- Md. Imam Uddin
- , Stephanie M. Evans
- & John S. Penn
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| Open AccessOxidized Low-density Lipoprotein (ox-LDL) Cholesterol Induces the Expression of miRNA-223 and L-type Calcium Channel Protein in Atrial Fibrillation
- Fengping He
- , Xin Xu
- & Jiaqiang Weng
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| Open AccessMetformin Enhances the Therapy Effects of Anti-IGF-1R mAb Figitumumab to NSCLC
- Hongxin Cao
- , Wei Dong
- & Jiajun Du
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| Open AccessRegulation of actin dynamics by WNT-5A: implications for human airway smooth muscle contraction
- Tim Koopmans
- , Kuldeep Kumawat
- & Reinoud Gosens
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| Open AccessHigh-density lipoprotein inhibits ox-LDL-induced adipokine secretion by upregulating SR-BI expression and suppressing ER Stress pathway
- Guohua Song
- , Xia Wu
- & Shucun Qin
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| Open AccessAltered protein phosphorylation as a resource for potential AD biomarkers
- Ana Gabriela Henriques
- , Thorsten Müller
- & Odete A. B. da Cruz e Silva
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| Open AccessLocal administration of siRNA through Microneedle: Optimization, Bio-distribution, Tumor Suppression and Toxicity
- Tao Tang
- , Yan Deng
- & Tony Kwok Hung Chung
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| Open AccessGenetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function
- Andre Kleensang
- , Marguerite M. Vantangoli
- & Thomas Hartung
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| Open AccessInsulin secretion impairment in Sirt6 knockout pancreatic β cells is mediated by suppression of the FoxO1-Pdx1-Glut2 pathway
- Mi-Young Song
- , Jie Wang
- & Byung-Hyun Park
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| Open AccessDengue virus infection induces interferon-lambda1 to facilitate cell migration
- Yu-Lin Hsu
- , Mei-Yi Wang
- & Jenn-Haung Lai
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| Open AccessProteomics of hot-wet and cold-dry temperaments proposed in Iranian traditional medicine: a Network-based Study
- Hassan Rezadoost
- , Mehrdad Karimi
- & Mohieddin Jafari
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| Open AccessRevisiting the mechanism of coagulation factor XIII activation and regulation from a structure/functional perspective
- Sneha Gupta
- , Arijit Biswas
- & Johannes Oldenburg
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| Open AccessA novel, rapid method to compare the therapeutic windows of oral anticoagulants using the Hill coefficient
- Jeremy B. Chang
- , Kayla M. Quinnies
- & Nicholas P. Tatonetti