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| Open AccessSynthetic Tet-inducible artificial microRNAs targeting β-catenin or HIF-1α inhibit malignant phenotypes of bladder cancer cells T24 and 5637
- Yonghao Zhan
- , Yuchen Liu
- & Zhiming Cai
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| Open AccessAffibody-mediated PET imaging of HER3 expression in malignant tumours
- Maria Rosestedt
- , Ken G. Andersson
- & Stefan Ståhl
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| Open AccessA Designed Angiopoietin-1 Variant, Dimeric CMP-Ang1 Activates Tie2 and Stimulates Angiogenesis and Vascular Stabilization in N-glycan Dependent Manner
- Nuri Oh
- , Kangsan Kim
- & Gou Young Koh
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| Open AccessDetermining the N-terminal orientations of recombinant transmembrane proteins in the Escherichia coli plasma membrane
- Chien-Hsien Lee
- , Chia-Cheng Chou
- & Andrew H.-J. Wang
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| Open AccessSynthesis of an arrayed sgRNA library targeting the human genome
- Tobias Schmidt
- , Jonathan L. Schmid-Burgk
- & Veit Hornung
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| Open AccessEnhanced nematicidal potential of the chitinase pachi from Pseudomonas aeruginosa in association with Cry21Aa
- Lin Chen
- , Huang Jiang
- & Ziduo Liu
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| Open AccessA Molecular Toolkit to Visualize Native Protein Assemblies in the Context of Human Disease
- Brian L. Gilmore
- , Carly E. Winton
- & Deborah F. Kelly
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| Open AccessEnhancing flavonoid production by systematically tuning the central metabolic pathways based on a CRISPR interference system in Escherichia coli
- Junjun Wu
- , Guocheng Du
- & Jingwen Zhou
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| Open AccessEngineering catechol 1, 2-dioxygenase by design for improving the performance of the cis, cis-muconic acid synthetic pathway in Escherichia coli
- Li Han
- , Pi Liu
- & Yanhe Ma
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| Open Accessl-Asparaginase from Streptomyces griseus NIOT-VKMA29: optimization of process variables using factorial designs and molecular characterization of l-asparaginase gene
- Balakrishnan Meena
- , Lawrance Anburajan
- & Ramalingam Kirubagaran
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| Open AccessPredominant structural configuration of natural antibody repertoires enables potent antibody responses against protein antigens
- Hong-Sen Chen
- , Shin-Chen Hou
- & An-Suei Yang
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| Open AccessArtificial targeting of misfolded cytosolic proteins to endoplasmic reticulum as a mechanism for clearance
- Fen Liu
- , Deanna M. Koepp
- & Kylie J. Walters
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| Open AccessTwo-photon directed evolution of green fluorescent proteins
- Caleb R. Stoltzfus
- , Lauren M. Barnett
- & Aleksander Rebane
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| Open AccessIn-vivo detection of binary PKA network interactions upon activation of endogenous GPCRs
- Ruth Röck
- , Verena Bachmann
- & Eduard Stefan
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| Open AccessA Phytophthora sojae cytoplasmic effector mediates disease resistance and abiotic stress tolerance in Nicotiana benthamiana
- Meixiang Zhang
- , Nasir Ahmed Rajput
- & Daolong Dou
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| Open AccessCRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
- Vyas Ramanan
- , Amir Shlomai
- & Sangeeta N. Bhatia
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| Open AccessA new target region for changing the substrate specificity of amine transaminases
- Li-Jun Guan
- , Jun Ohtsuka
- & Masaru Tanokura
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| Open AccessRiboTALE: A modular, inducible system for accurate gene expression control
- Navneet Rai
- , Aura Ferreiro
- & Ilias Tagkopoulos
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| Open AccessAn overhang-based DNA block shuffling method for creating a customized random library
- Kosuke Fujishima
- , Chris Venter
- & Lynn J. Rothschild
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| Open AccessProtein stabilization utilizing a redefined codon
- Kazumasa Ohtake
- , Atsushi Yamaguchi
- & Kensaku Sakamoto
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| Open AccessHighly reproductive Escherichia coli cells with no specific assignment to the UAG codon
- Takahito Mukai
- , Hiroko Hoshi
- & Kensaku Sakamoto
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| Open AccessAntibacterial activity of silver-killed bacteria: the "zombies" effect
- Racheli Ben-Knaz Wakshlak
- , Rami Pedahzur
- & David Avnir
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| Open AccessA platform for rapid generation of single and multiplexed reporters in human iPSC lines
- Ying Pei
- , Guadalupe Sierra
- & Xianmin Zeng
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| Open AccessRational stabilization of complex proteins: a divide and combine approach
- Emilio Lamazares
- , Isabel Clemente
- & Javier Sancho
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| Open AccessAn efficient strategy for producing a stable, replaceable, highly efficient transgene expression system in silkworm, Bombyx mori
- Dingpei Long
- , Weijian Lu
- & Aichun Zhao
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| Open AccessA Dual-Intein Autoprocessing Domain that Directs Synchronized Protein Co-Expression in Both Prokaryotes and Eukaryotes
- Bei Zhang
- , Madhusudhan Rapolu
- & Wei Wen Su
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| Open AccessOptimized tuning of TALEN specificity using non-conventional RVDs
- Alexandre Juillerat
- , Coline Pessereau
- & Philippe Duchateau
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| Open AccessAn engineered genetic selection for ternary protein complexes inspired by a natural three-component hitchhiker mechanism
- Hyeon-Cheol Lee
- , Alyse D. Portnoff
- & Matthew P. DeLisa
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| Open AccessConstruction of a Hypervirulent and Specific Mycoinsecticide for Locust Control
- Weiguo Fang
- , Hsiao-Ling Lu
- & Raymond J. St. Leger
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| Open AccessA novel mechanism of protein thermostability: a unique N-terminal domain confers heat resistance to Fe/Mn-SODs
- Wei Wang
- , Ting Ma
- & Jiansong Cheng
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| Open AccessGenome editing of BmFib-H gene provides an empty Bombyx mori silk gland for a highly efficient bioreactor
- Sanyuan Ma
- , Run Shi
- & Qingyou Xia
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| Open AccessIn vitro nanobody discovery for integral membrane protein targets
- Rupak Doshi
- , Beverly R. Chen
- & Geoffrey Chang
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| Open AccessCell-surface receptor control that depends on the size of a synthetic equilateral-triangular RNA-protein complex
- Yoshihiko Fujita
- , Rie Furushima
- & Tan Inoue
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| Open AccessDetecting protein–protein interactions based on kinase-mediated growth induction of mammalian cells
- Satoru Mabe
- , Teruyuki Nagamune
- & Masahiro Kawahara
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| Open AccessA tool kit for rapid cloning and expression of recombinant antibodies
- Tihomir S. Dodev
- , Panagiotis Karagiannis
- & Andrew J. Beavil
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| Open AccessProtein engineering of selected residues from conserved sequence regions of a novel Anoxybacillus α-amylase
- Velayudhan Ranjani
- , Štefan Janeček
- & Kian Mau Goh
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| Open AccessIdentification and use of an alkane transporter plug-in for applications in biocatalysis and whole-cell biosensing of alkanes
- Chris Grant
- , Dawid Deszcz
- & Frank Baganz
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| Open AccessSuccinate production from CO2-grown microalgal biomass as carbon source using engineered Corynebacterium glutamicum through consolidated bioprocessing
- Jungseok Lee
- , Sang Jun Sim
- & Han Min Woo
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| Open AccessThe tetrapeptide core of the carrier peptide Xentry is cell-penetrating: novel activatable forms of Xentry
- Kristopher Montrose
- , Yi Yang
- & Geoffrey W. Krissansen
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| Open AccessCRISPR/Cas9 mediated multiplex genome editing and heritable mutagenesis of BmKu70 in Bombyx mori
- Sanyuan Ma
- , Jiasong Chang
- & Qingyou Xia
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| Open AccessBurrH: a new modular DNA binding protein for genome engineering
- Alexandre Juillerat
- , Claudia Bertonati
- & Philippe Duchateau
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| Open AccessAffinity improvement of a therapeutic antibody to methamphetamine and amphetamine through structure-based antibody engineering
- Shraddha Thakkar
- , Nisha Nanaware-Kharade
- & Kottayil I. Varughese
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| Open AccessKnockout of an endogenous mannosyltransferase increases the homogeneity of glycoproteins produced in Pichia pastoris
- Florian W. Krainer
- , Christoph Gmeiner
- & Oliver Spadiut
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| Open AccessLinking genotype to phenotype on beads: high throughput selection of peptides with biological function
- Li-Chieh Huang
- , Xiaoyan Pan
- & Graham Ogg
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| Open AccessA New Protein-Protein Interaction Sensor Based on Tripartite Split-GFP Association
- Stéphanie Cabantous
- , Hau B. Nguyen
- & Geoffrey S. Waldo
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| Open AccessConferring the ability to utilize inorganic polyphosphate on ATP-specific NAD kinase
- Yusuke Nakamichi
- , Aya Yoshioka
- & Kousaku Murata
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| Open AccessExtended Stokes Shift in Fluorescent Proteins: Chromophore–Protein Interactions in a Near-Infrared TagRFP675 Variant
- Kiryl D. Piatkevich
- , Vladimir N. Malashkevich
- & Vladislav V. Verkhusha
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| Open AccessImproved adeno-associated virus (AAV) serotype 1 and 5 vectors for gene therapy
- Dwaipayan Sen
- , Balaji Balakrishnan
- & Giridhara R. Jayandharan
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| Open AccessChaperone-assisted thermostability engineering of a soluble T cell receptor using phage display
- Kristin S. Gunnarsen
- , Solveig G. Kristinsson
- & Geir Åge Løset