Molecular biology

Molecular Biology is the field of biology that studies the composition, structure and interactions of cellular molecules such as nucleic acids and proteins that carry out the biological processes essential for the cells functions and maintenance.

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News & Views | 30 June 2022

Don’t put all your epigenetic eggs in one basket
- Nicole M. Bush
- & Craig P. Hunter
Nature Cell Biology, 1-3
News & Views | 27 June 2022

Changes in the expression profiles of oligodendrocytes are shared in different brain pathologies

Nature Neuroscience, 1-2
News & Views | 13 June 2022

PRC2 shields the potency of human stem cells
- Sergi Aranda
- , Livia Condemi
- & Luciano Di Croce
Nature Cell Biology 24, 806-808

Latest Research and Reviews

Research
04 July 2022 | Open Access

Hypoxia-hindered methylation of PTGIS in endometrial stromal cells accelerates endometriosis progression by inducing CD16⁻ NK-cell differentiation
- Haiyan Peng
- , Lichun Weng
- & Dong Zhao
Experimental & Molecular Medicine, 1-16
Research
03 July 2022 | Open Access

Genome-wide identification and in silico analysis of NPF, NRT2, CLC and SLAC1/SLAH nitrate transporters in hexaploid wheat (Triticum aestivum)
- Aman Kumar
- , Nitika Sandhu
- & Parveen Chhuneja
Scientific Reports 12, 11227
Research
01 July 2022 | Open Access

Amelioration for an ignored pitfall in reference gene selection by considering the mean expression and standard deviation of target genes
- Ghazal Esfandiarpour
- , Mohammad Mokhtari
- & Ahmed Almuslimawi
Scientific Reports 12, 11129
Research
01 July 2022 | Open Access

Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria

How bacteria sense and respond to nitrogen is a key question in microbial physiology. This work unveils the mechanism by which the central nitrogen metabolic enzyme, glutamine synthetase, directly signals nitrogen availability to the GlnR regulator.
- Brady A. Travis
- , Jared V. Peck
- & Maria A. Schumacher
Nature Communications 13, 3793
Research
01 July 2022 | Open Access

Dissecting the roles of Haspin and VRK1 in histone H3 phosphorylation during mitosis
- Tyrell N. Cartwright
- , Rebecca J. Harris
- & Jonathan M. G. Higgins
Scientific Reports 12, 11210
Research
01 July 2022 | Open Access

Interleukin 7 inhibit autophagy via P53 regulated AMPK/mTOR signaling pathway in non-small cell lung cancer
- Yunjia Zhu
- , Xi Jiang
- & Jian Ming
Scientific Reports 12, 11208

All Research & Reviews

News and Comment

Research Highlights | 30 June 2022

Principles of mRNA destruction

Olivia Rissland recounts the findings of a paper that was seminal to our understanding of mRNA decay.
- Olivia S. Rissland
Nature Reviews Molecular Cell Biology, 1
News & Views | 30 June 2022

Don’t put all your epigenetic eggs in one basket

In Caenorhabditis elegans, RNAi-initiated gene silencing can persist for multiple generations. A study shows that this heritable silencing requires parallel contributions of both a nuclear transcriptional silencing pathway and perinuclear condensate-localized poly(UG)-tailed transcripts to produce abundant germline siRNAs in adult progeny.
- Nicole M. Bush
- & Craig P. Hunter
Nature Cell Biology, 1-3
Research Highlights | 27 June 2022

Bacterial data loggers
- Kate de Mattos-Shipley
Nature Chemical Biology 18, 679
News & Views | 27 June 2022

Changes in the expression profiles of oligodendrocytes are shared in different brain pathologies

A new cell state of disease-associated oligodendrocytes (DOLs) has been identified, which presents a transcriptional program that is probably driven by neuroinflammation and is shared among different non-immune glial cells across multiple pathologies of the central nervous system.

Nature Neuroscience, 1-2
Comments & Opinion | 23 June 2022

Supporting scientists who are deaf or hard of hearing

Increasing awareness and better technology bodes for a more positive future for scientists who are deaf or hard of hearing, explains John Dennehy.
- John J. Dennehy
Nature Microbiology, 1
Research Highlights | 21 June 2022

ncRNA regulation of mitochondrial transcription

The non-coding RNA 7S inhibits transcription initiation in mitochondria by preventing the RNA polymerase from interacting with promoter DNA and transcription factors.
- Eytan Zlotorynski
Nature Reviews Molecular Cell Biology, 1

All News & Comment

Molecular biology

Featured

Don’t put all your epigenetic eggs in one basket

Changes in the expression profiles of oligodendrocytes are shared in different brain pathologies

PRC2 shields the potency of human stem cells

Latest Research and Reviews

Hypoxia-hindered methylation of PTGIS in endometrial stromal cells accelerates endometriosis progression by inducing CD16⁻ NK-cell differentiation

Genome-wide identification and in silico analysis of NPF, NRT2, CLC and SLAC1/SLAH nitrate transporters in hexaploid wheat (Triticum aestivum)

Amelioration for an ignored pitfall in reference gene selection by considering the mean expression and standard deviation of target genes

Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria

Dissecting the roles of Haspin and VRK1 in histone H3 phosphorylation during mitosis

Interleukin 7 inhibit autophagy via P53 regulated AMPK/mTOR signaling pathway in non-small cell lung cancer

News and Comment

Principles of mRNA destruction

Don’t put all your epigenetic eggs in one basket

Bacterial data loggers

Changes in the expression profiles of oligodendrocytes are shared in different brain pathologies

Supporting scientists who are deaf or hard of hearing

ncRNA regulation of mitochondrial transcription

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