Featured
-
-
Article
| Open AccessReduction of spermine synthase enhances autophagy to suppress Tau accumulation
- Xianzun Tao
- , Jiaqi Liu
- & R. Grace Zhai
-
Article
| Open AccessAntibiotics treatment promotes vasculogenesis in the brain of glioma-bearing mice
- Maria Rosito
- , Javeria Maqbool
- & Cristina Limatola
-
Article
| Open AccessAldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect
- Yu-De Chu
- , Li-Chun Cheng
- & Wey-Ran Lin
-
Article
| Open AccessInhibition of mitochondrial fission activates glycogen synthesis to support cell survival in colon cancer
- Sumati Hasani
- , Lyndsay E. A. Young
- & Tianyan Gao
-
Article
| Open AccessIntracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells
- Flore Sneyers
- , Martijn Kerkhofs
- & Geert Bultynck
-
Article
| Open AccessIF1 ablation prevents ATP synthase oligomerization, enhances mitochondrial ATP turnover and promotes an adenosine-mediated pro-inflammatory phenotype
- Sonia Domínguez-Zorita
- , Inés Romero-Carramiñana
- & José M. Cuezva
-
Article
| Open AccessLipid desaturation regulates the balance between self-renewal and differentiation in mouse blastocyst-derived stem cells
- Chanchal Thomas Mannully
- , Reut Bruck-Haimson
- & Arieh Moussaieff
-
Article
| Open AccessMetabolic regulation of cholestatic liver injury by D-2-hydroxyglutarate with the modulation of hepatic microenvironment and the mammalian target of rapamycin signaling
- Xinbei Tian
- , Ying Wang
- & Yongtao Xiao
-
Article
| Open AccessCt-OATP1B3 promotes high-grade serous ovarian cancer metastasis by regulation of fatty acid beta-oxidation and oxidative phosphorylation
- Yutang Huang
- , Yan Du
- & Lanxiang Wu
-
Article
| Open AccessSex differences in global metabolomic profiles of COVID-19 patients
- Rocio Diaz Escarcega
- , Pedram Honarpisheh
- & Andrey S. Tsvetkov
-
Article
| Open AccessAn integrated bioinformatic investigation of mitochondrial solute carrier family 25 (SLC25) in colon cancer followed by preliminary validation of member 5 (SLC25A5) in tumorigenesis
- Yan-Jie Chen
- , Wei-Feng Hong
- & Li Liang
-
Article
| Open AccessAlterations in the gut microbiota and metabolite profiles of patients with Kashin-Beck disease, an endemic osteoarthritis in China
- Xi Wang
- , Yujie Ning
- & Xiong Guo
-
Article
| Open AccessParp mutations protect from mitochondrial toxicity in Alzheimer’s disease
- Yizhou Yu
- , Giorgio Fedele
- & L. Miguel Martins
-
Article
| Open AccessCeramides and sphingosine-1-phosphate mediate the distinct effects of M1/M2-macrophage infusion on liver recovery after hepatectomy
- Hang Sun
- , Shibo Sun
- & Kai Wang
-
Article
| Open AccessS-adenosylmethionine upregulates the angiotensin receptor-binding protein ATRAP via the methylation of HuR in NAFLD
- Tao Guo
- , Zhe Dai
- & Zhen Li
-
Article
| Open AccessMetabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkers
- François-Xavier Danlos
- , Claudia Grajeda-Iglesias
- & Guido Kroemer
-
Article
| Open AccessVenetoclax causes metabolic reprogramming independent of BCL-2 inhibition
- Alba Roca-Portoles
- , Giovanny Rodriguez-Blanco
- & Stephen W. G. Tait
-
Article
| Open AccessGADD45α drives brown adipose tissue formation through upregulating PPARγ in mice
- Wenjing You
- , Ziye Xu
- & Tizhong Shan
-
Article
| Open AccessHexokinase 2 is dispensable for photoreceptor development but is required for survival during aging and outer retinal stress
- Eric Weh
- , Zuzanna Lutrzykowska
- & Cagri G. Besirli
-
Article
| Open AccessFormate induces a metabolic switch in nucleotide and energy metabolism
- Kristell Oizel
- , Jacqueline Tait-Mulder
- & Alexei Vazquez
-
Article
| Open AccessThe heterocyclic compound Tempol inhibits the growth of cancer cells by interfering with glutamine metabolism
- Shuangyan Ye
- , Pengfei Xu
- & Qiuzhen Liu
-
Article
| Open AccessEnhanced fatty acid oxidation provides glioblastoma cells metabolic plasticity to accommodate to its dynamic nutrient microenvironment
- Shiva Kant
- , Pravin Kesarwani
- & Prakash Chinnaiyan
-
Article
| Open AccessCombinatorial targeting of MTHFD2 and PAICS in purine synthesis as a novel therapeutic strategy
- Chantal Hoi Yin Cheung
- , Chia-Lang Hsu
- & Hsueh-Fen Juan
-
Article
| Open AccessThymidine phosphorylase promotes malignant progression in hepatocellular carcinoma through pentose Warburg effect
- Qiang Zhang
- , Yuan Qin
- & Cheng Yang
-
Original Article
| Open AccessTranscriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP+
- A K Krug
- , S Gutbier
- & M Leist