Featured
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| Open AccessInfluence of body mass index on incidence and prognosis of acute myeloid leukemia and acute promyelocytic leukemia: A meta-analysis
- Shufen Li
- , Li Chen
- & Kankan Wang
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| Open AccessProbing the requirement for CD38 in retinoic acid-induced HL-60 cell differentiation with a small molecule dimerizer and genetic knockout
- Robert J. MacDonald
- , Jonathan H. Shrimp
- & Andrew Yen
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| Open AccessLck is a relevant target in chronic lymphocytic leukaemia cells whose expression variance is unrelated to disease outcome
- Kathleen J. Till
- , John C. Allen
- & Joseph R. Slupsky
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| Open AccessAutonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells
- Ken Morita
- , Mina Noura
- & Yasuhiko Kamikubo
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| Open AccessRevisiting the role of interleukin-8 in chronic lymphocytic leukemia
- Denise Risnik
- , Enrique Podaza
- & Mirta Giordano
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| Open AccessTargeting c-KIT (CD117) by dasatinib and radotinib promotes acute myeloid leukemia cell death
- Sook-Kyoung Heo
- , Eui-Kyu Noh
- & Hawk Kim
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| Open AccessThe EphB6 receptor is overexpressed in pediatric T cell acute lymphoblastic leukemia and increases its sensitivity to doxorubicin treatment
- Amr El Zawily
- , Emily McEwen
- & Andrew Freywald
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| Open AccessFunctional Activation of Osteoclast Commitment in Chronic Lymphocytic Leukaemia: a Possible Role for RANK/RANKL Pathway
- Cecilia Marini
- , Silvia Bruno
- & Gianmario Sambuceti
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| Open AccessThe Src family kinase LCK cooperates with oncogenic FLT3/ITD in cellular transformation
- Alissa Marhäll
- , Julhash U. Kazi
- & Lars Rönnstrand
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| Open AccessA novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression
- Abhishek Mangaonkar
- , Ashis Kumar Mondal
- & Ravindra Kolhe
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| Open AccessProtein interaction network of alternatively spliced NudCD1 isoforms
- Patrick Asselin-Mullen
- , Anaïs Chauvin
- & François-Michel Boisvert
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| Open AccessThe autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells
- Anna M. Schläfli
- , Pauline Isakson
- & Mario P. Tschan
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| Open AccessHTLV-1 bZIP factor suppresses TDP1 expression through inhibition of NRF-1 in adult T-cell leukemia
- Yoko Takiuchi
- , Masayuki Kobayashi
- & Akifumi Takaori-Kondo
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| Open AccessMicroenvironment regulates the expression of miR-21 and tumor suppressor genes PTEN, PIAS3 and PDCD4 through ZAP-70 in chronic lymphocytic leukemia
- Júlia Carabia
- , Cecilia Carpio
- & Marta Crespo
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| Open AccessA Phase II Study of Arginine Deiminase (ADI-PEG20) in Relapsed/Refractory or Poor-Risk Acute Myeloid Leukemia Patients
- Hui-Jen Tsai
- , Shih Sheng Jiang
- & Tsai-Yun Chen
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| Open AccessPrognostic significance of high GFI1 expression in AML of normal karyotype and its association with a FLT3-ITD signature
- Giacomo Volpe
- , David S. Walton
- & Jon Frampton
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Article
| Open AccessImmunoregulation by IL-7R-targeting antibody-drug conjugates: overcoming steroid-resistance in cancer and autoimmune disease
- Masahiro Yasunaga
- , Shino Manabe
- & Yasuhiro Matsumura
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| Open AccessDiscovery of human-like L-asparaginases with potential clinical use by directed evolution
- Coraline Rigouin
- , Hien Anh Nguyen
- & Arnon Lavie
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| Open AccessEfficacy and safety of different doses of cytarabine in consolidation therapy for adult acute myeloid leukemia patients: a network meta-analysis
- Di Wu
- , Chongyang Duan
- & Size Chen
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| Open AccessComprehensive miRNA expression profiling in human T-cell acute lymphoblastic leukemia by small RNA-sequencing
- Annelynn Wallaert
- , Wouter Van Loocke
- & Pieter Van Vlierberghe
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| Open AccessTargeting primary acute myeloid leukemia with a new CXCR4 antagonist IgG1 antibody (PF-06747143)
- Yanyan Zhang
- , Erika Saavedra
- & Fawzia Louache
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| Open AccessImipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells
- Jonathan Metts
- , Heath L. Bradley
- & Kevin D. Bunting
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| Open AccessRole of new Immunophenotypic Markers on Prognostic and Overall Survival of Acute Myeloid Leukemia: a Systematic Review and Meta-Analysis
- A. F. O. Costa
- , D. L. Menezes
- & D. M. Schimieguel
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| Open AccessPP2A inhibition from LB100 therapy enhances daunorubicin cytotoxicity in secondary acute myeloid leukemia via miR-181b-1 upregulation
- Chao Hu
- , Mengxia Yu
- & Hongyan Tong
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| Open AccessIdentification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia
- Mattia Mori
- , Luca Tottone
- & Rocco Palermo
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| Open AccessSuper-Enhancers and Broad H3K4me3 Domains Form Complex Gene Regulatory Circuits Involving Chromatin Interactions
- Fan Cao
- , Yiwen Fang
- & Melissa J. Fullwood
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| Open AccessALOX5 exhibits anti-tumor and drug-sensitizing effects in MLL-rearranged leukemia
- Yungui Wang
- , Jennifer R. Skibbe
- & Xi Jiang
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| Open AccessCordycepin disrupts leukemia association with mesenchymal stromal cells and eliminates leukemia stem cell activity
- Shu-Man Liang
- , Yi-Jhu Lu
- & Jun-Yang Liou
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| Open AccessTargeting Thioredoxin-1 by dimethyl fumarate induces ripoptosome-mediated cell death
- Anne Schroeder
- , Uwe Warnken
- & Karsten Gülow
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Article
| Open AccessTranscriptional mechanism of vascular endothelial growth factor-induced expression of protein kinase CβII in chronic lymphocytic leukaemia cells
- Ola Al-Sanabra
- , Andrew D. Duckworth
- & Joseph R. Slupsky
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| Open AccessMechanisms responsible for the synergistic antileukemic interactions between ATR inhibition and cytarabine in acute myeloid leukemia cells
- Jun Ma
- , Xinyu Li
- & Yubin Ge
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| Open AccessDe novo AML exhibits greater microenvironment dysregulation compared to AML with myelodysplasia-related changes
- Matheus Rodrigues Lopes
- , João Kleber Novais Pereira
- & Patricia Favaro
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| Open AccessUse of PEG-asparaginase in newly diagnosed adults with standard-risk acute lymphoblastic leukemia compared with E. coli-asparaginase: a retrospective single-center study
- Wen-jian Liu
- , Hua Wang
- & Yue Lu
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| Open AccessTargeting High Dynamin-2 (DNM2) Expression by Restoring Ikaros Function in Acute Lymphoblastic Leukemia
- Zheng Ge
- , Yan Gu
- & Chunhua Song
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| Open AccessRecombinant L-asparaginase 1 from Saccharomyces cerevisiae: an allosteric enzyme with antineoplastic activity
- Iris Munhoz Costa
- , Leonardo Schultz
- & Gisele Monteiro
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Article
| Open AccessUsing genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML
- Morito Kurata
- , Susan K. Rathe
- & David A. Largaespada
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Article
| Open AccessIntramolecular hydrophobic interactions are critical mediators of STAT5 dimerization
- Dirk Fahrenkamp
- , Jinyu Li
- & Gerhard Müller-Newen
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| Open AccessCyr61 participates in the pathogenesis of acute lymphoblastic leukemia by enhancing cellular survival via the AKT/NF-κB signaling pathway
- Xianjin Zhu
- , Yanfang Song
- & Ningli Li
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| Open AccessAML1/ETO accelerates cell migration and impairs cell-to-cell adhesion and homing of hematopoietic stem/progenitor cells
- Marco Saia
- , Alberto Termanini
- & Myriam Alcalay
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| Open AccessDeciphering KRAS and NRAS mutated clone dynamics in MLL-AF4 paediatric leukaemia by ultra deep sequencing analysis
- Luca Trentin
- , Silvia Bresolin
- & Giuseppe Basso
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| Open AccessHigh expression of MAP7 predicts adverse prognosis in young patients with cytogenetically normal acute myeloid leukemia
- Lin Fu
- , Huaping Fu
- & Jinlong Shi
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| Open AccessExpression of immunoproteasome genes is regulated by cell-intrinsic and –extrinsic factors in human cancers
- Alexandre Rouette
- , Assya Trofimov
- & Claude Perreault
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| Open AccessUrsolic acid-mediated apoptosis of K562 cells involves Stat5/Akt pathway inhibition through the induction of Gfi-1
- Ze Lin
- , Jikai Jiang
- & Xiao-Shan Liu
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| Open AccessSIRT2 activates G6PD to enhance NADPH production and promote leukaemia cell proliferation
- Shuang-Nian Xu
- , Tian-Shi Wang
- & Yi-Ping Wang
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| Open AccessIdentification and functional characterization of the miRNA-gene regulatory network in chronic myeloid leukemia lineage negative cells
- S. Agatheeswaran
- , N. C. Pattnayak
- & S. Chakraborty
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| Open AccessThe oncometabolite R-2-hydroxyglutarate activates NF-κB-dependent tumor-promoting stromal niche for acute myeloid leukemia cells
- Jing-Yi Chen
- , You-Syuan Lai
- & Wen-Chun Hung
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| Open AccessMiR-146b negatively regulates migration and delays progression of T-cell acute lymphoblastic leukemia
- Nádia C. Correia
- , Rita Fragoso
- & João T. Barata
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| Open AccessFibroblast Growth Factor-2 facilitates the growth and chemo-resistance of leukemia cells in the bone marrow by modulating osteoblast functions
- Keiki Sugimoto
- , Yasuhiko Miyata
- & Tomoki Naoe
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| Open AccessPACSIN2 polymorphism is associated with thiopurine-induced hematological toxicity in children with acute lymphoblastic leukaemia undergoing maintenance therapy
- Alenka Smid
- , Natasa Karas-Kuzelicki
- & Irena Mlinaric-Rascan