Lamination articles within Nature Communications

Featured

• Article
  27 September 2023 | Open Access

  Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex

  While progress in early human cortical development is acknowledged, a limited understanding persists regarding transcriptomic and translational profiles in subplate neurons. Here, the authors discovered an enrichment of autism spectrum disorder risk genes in subplate neurons, underscoring the crucial role played by the RNA-binding protein CELF4 in translating synaptic mRNAs during neocortical development.

  • Iva Salamon
  • , Yongkyu Park
  •  & Mladen-Roko Rasin

• Article
  08 January 2018 | Open Access

  Injured adult motor and sensory axons regenerate into appropriate organotypic domains of neural progenitor grafts

  Understanding how transplanted cells interact with the host nervous system will be important for cell based neural regeneration approaches. Here, the authors study the sensory fate of neural progenitor cell grafts transplanted to the injured spinal cord, and show that host axons retain the ability to distinguish appropriate and inappropriate graft targets.

  • Jennifer N. Dulin
  • , Andrew F. Adler
  •  & Mark H. Tuszynski

• Article
  27 October 2017 | Open Access

  Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior

  Functional consequence of transient delay in neuronal migration is unclear. This study shows that Wnt/C-Kit signaling regulates radial migration in rat somatosensory cortex, and that transient delay of L2/3 neuronal migration leads to interhemispheric connectivity alteration and abnormal social behavior.

  • Riccardo Bocchi
  • , Kristof Egervari
  •  & Jozsef Z. Kiss

• Article
  23 February 2017 | Open Access

  Drebrin-mediated microtubule–actomyosin coupling steers cerebellar granule neuron nucleokinesis and migration pathway selection

  Neuronal migration is vital for neuronal circuit morphogenesis and is thought to rely on microtubule-actomyosin crosstalk. Here, the authors use super-resolution imaging and the drebrin microtubule-actin crosslinking protein to show that microtubule-actomyosin coupling controls the direction of centrosome and somal motility.

  • Niraj Trivedi
  • , Daniel R. Stabley
  •  & David J. Solecki