Information theory articles within Nature Communications

Featured

• Article
  24 February 2021 | Open Access

  Quantifying information accumulation encoded in the dynamics of biochemical signaling

  Understanding how cells discriminate between stimuli is an ongoing challenge. Here, the authors propose a mathematical framework for inferring the mutual information encoded in temporal signaling dynamics and use it to study how information is transmitted over time in response to different stimuli in NFκB, MAPK and p53 signaling pathways.

  • Ying Tang
  • , Adewunmi Adelaja
  •  & Alexander Hoffmann

• Article
  08 April 2020 | Open Access

  DNA punch cards for storing data on native DNA sequences via enzymatic nicking

  Current synthetic DNA-based data storage systems have high recording costs, read-write latency and error-rates that make them uncompetitive compared to traditional digital storage. The authors use nicks in native DNA to encode data in parallel and create access sites for in-memory computations.

  • S. Kasra Tabatabaei
  • , Boya Wang
  •  & Olgica Milenkovic

• Article
  13 August 2019 | Open Access

  Information-based centralization of locomotion in animals and robots

  Model-based centralization schemes, though able to quantify locomotion control in animals and bio-inspired robots, are limited to specific systems. Here, the authors report a generalized information-based centralization scheme that unifies existing models and can be applied to different systems.

  • Izaak D. Neveln
  • , Amoolya Tirumalai
  •  & Simon Sponberg

• Article
  02 November 2018 | Open Access

  An information-theoretic framework for deciphering pleiotropic and noisy biochemical signaling

  Signalling responses are marked by substantial cell-to-cell variability. Here, the authors propose an information theoretic framework that accounts for multiple inputs and temporal dynamics to analyse how signals flow through shared network components.

  • Tomasz Jetka
  • , Karol Nienałtowski
  •  & Michał Komorowski

• Article
  28 February 2018 | Open Access

  High capacity in G protein-coupled receptor signaling

  G protein-coupled receptors (GPCRs) activate intracellular signalling pathways upon extracellular stimulation. Here authors record single cell responses of GPCR signalling which allows the direct estimation of its channel capacity for each cell along with the reproducibility of its response.

  • Amiran Keshelava
  • , Gonzalo P. Solis
  •  & Vladimir L. Katanaev