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PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity
AUF1 is an RNA-binding protein believed to function mostly by regulating the decay of its target transcripts. Here, Yoon et al.systematically identify the targets of AUF1 and provide insights into how AUF1 functions to regulate various cellular processes by enhancing the decay, stability or translation of specific RNAs.
- Je-Hyun Yoon
- , Supriyo De
- & Myriam Gorospe