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A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus
While Hodgkin lymphoma (HL) is a common cancer affecting young adults in Western countries, its genetic basis is poorly understood. Here, the authors carry out a genome-wide association analysis in HL patients and healthy controls; identifying a new HL risk locus and implicating TCF3in the disease aetiology.
- W. Cozen
- , M. N. Timofeeva
- & J. D. McKay
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Variation at 3p24.1 and 6q23.3 influences the risk of Hodgkin’s lymphoma
Hodgkin’s lymphoma has a genetic component that is poorly understood. In this study, Frampton et al. perform a genome-wide association study in German patients and combine the results with a previously published UK genome-wide association study to identify susceptibility loci at 3p24.1 and 6q23.3.
- Matthew Frampton
- , Miguel Inacio da Silva Filho
- & Richard S. Houlston